Welcome to chemicalbook!
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook > Product Catalogue >API >Specialty drugs >Dermatology drugs >Tazarotene

Tazarotene

Tazarotene Structure
  • ₹5409 - ₹39900.95
  • Product name: Tazarotene
  • CAS: 118292-40-3
  • MF: C21H21NO2S
  • MW: 351.46
  • EINECS:601-516-4
  • MDL Number:MFCD00867628
  • Synonyms:3-pyridinecarboxylicacid,6-((3,4-dihydro-4,4-dimethyl-2h-1-benzothiopyran-6-y ;agn190168 ;6-[(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran)-6-yl]nicotinic acid ethyl ester;Tazorac/zorac;6-[2-(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]- 3-pyridinecarboxylic Acid Ethyl Ester;Tazorac;Zorac;Tazarotene(Avage)
6 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 10MG
  • 50MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberT3108
  • Product descriptionTazarotene min. 98.0 %
  • Packaging10MG
  • Price₹6100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT3108
  • Product descriptionTazarotene min. 98.0 %
  • Packaging100MG
  • Price₹18900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7080
  • Product descriptionTazarotene ≥98% (HPLC)
  • Packaging10MG
  • Price₹9536.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7080
  • Product descriptionTazarotene ≥98% (HPLC)
  • Packaging50MG
  • Price₹39900.95
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number T 3256
  • Product descriptionTazarotene, ≥98% (HPLC)
  • Packaging10mg
  • Price₹5409
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number T 3256
  • Product descriptionTazarotene, ≥98% (HPLC)
  • Packaging100mg
  • Price₹18900
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T3108 Tazarotene min. 98.0 % 10MG ₹6100 2022-05-26 Buy
TCI Chemicals (India) T3108 Tazarotene min. 98.0 % 100MG ₹18900 2022-05-26 Buy
Sigma-Aldrich(India) T7080 Tazarotene ≥98% (HPLC) 10MG ₹9536.83 2022-06-14 Buy
Sigma-Aldrich(India) T7080 Tazarotene ≥98% (HPLC) 50MG ₹39900.95 2022-06-14 Buy
ottokemi T 3256 Tazarotene, ≥98% (HPLC) 10mg ₹5409 2022-05-26 Buy
ottokemi T 3256 Tazarotene, ≥98% (HPLC) 100mg ₹18900 2022-05-26 Buy

Properties

Melting point :95-98°C
Boiling point :499.8±45.0 °C(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >15mg/mL
pka :0.04±0.29(Predicted)
form :powder
color :white to very faintly yellow
Merck :14,9081
CAS DataBase Reference :118292-40-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Tazarotene belongs to a third generation prescription topical retinoid. It is marketed in different forms including cream (brand name: Avage), foam (brand name: Fabuir) and gel (brand name: Tazorac). It is mainly used for the treatment of psoriasis, acne, and sun damaged skin. The detailed mechanisms of action of Tazarotene are still unclear. It is converted to its active form, the cognate carboxylic acid of tazarotene (AGN 190299) in vivo through rapid de-esterification in animals and man. AGN 190299 is capable of binding to all the three members of the retinoic acid receptor (RAR) family: RARα, RARβ, and RARγ with relative selectivity for RARβ, and RARγ. This process may further modify gene expression. However, it is unclear whether this is related to its mode of action. Common side effects associated with it include worsening of acne, desquamation, burning/stinging, erythema and pruritus increased sensitivity to sunlight, dry skin, itchiness, redness, skin pain rash and skin discoloration. In most cases, these side effects are mild and can remarkable decrease after the first 2–4 weeks. Tazarotene should not be used in the following cases: patients are allergic to it; patients are pregnant; patients have a sunburn; patients are taking photo-sensitive drugs such as thiazides and tetracycline.

Related product price