Tazarotene
- CAS No.
- 118292-40-3
- Chemical Name:
- Tazarotene
- Synonyms
- Avage;Zorac;Tazorac;agn190168;azarotene;TAZAROTENE;Tazorac/zorac;Tazarotene(Avage);Tazarotene, >=98%;Tazarotene 99% Min
- CBNumber:
- CB7405439
- Molecular Formula:
- C21H21NO2S
- Molecular Weight:
- 351.46
- MOL File:
- 118292-40-3.mol
- Modify Date:
- 2024/4/29 14:28:21
| Melting point | 95-98°C |
|---|---|
| Boiling point | 499.8±45.0 °C(Predicted) |
| Density | 1.22±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >15mg/mL |
| pka | 0.04±0.29(Predicted) |
| form | powder |
| color | white to very faintly yellow |
| Merck | 14,9081 |
| CAS DataBase Reference | 118292-40-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H361d | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | US5675100 | |||||||||
| HS Code | 2934.99.3000 | |||||||||
| NFPA 704 |
|
Tazarotene price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T7080 | Tazarotene ≥98% (HPLC) | 118292-40-3 | 10MG | ₹9536.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7080 | Tazarotene ≥98% (HPLC) | 118292-40-3 | 50MG | ₹39900.95 | 2022-06-14 | Buy |
| TCI Chemicals (India) | T3108 | Tazarotene min. 98.0 % | 118292-40-3 | 10MG | ₹6100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T3108 | Tazarotene min. 98.0 % | 118292-40-3 | 100MG | ₹18900 | 2022-05-26 | Buy |
| ottokemi | T 3256 | Tazarotene, ≥98% (HPLC) | 118292-40-3 | 10mg | ₹5409 | 2022-05-26 | Buy |
Tazarotene Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Tazarotene is a prescription topical retinoid sold as a cream or gel. This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage). It is commonly sold in two concentrations: 0.05% and 0.1%. In addition to tretinoin, wh
Indications
Like other retinoids, tazarotene (Tazorac) acts by binding to RARs and altering gene expression. Tazarotene appears to be particularly selective for the retinoid receptors RAR-β and RAR-γ, but the clinical significance of this observation is unknown.
Definition
ChEBI: The ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin.
Clinical Use
In the United States, tazarotene has been approved for topical treatment of psoriasis (involving up to 20% body surface area) and mild to moderate facial acne. Application site burning, stinging, and desquamation are common side effects, especially with acne. Tazarotene is contraindicated in women who are pregnant.
Side effects
Tazorac is a category X drug and must be avoided in pregnancy. This drug can be irritating and should be avoided in patients with sensitive skin or seborrheic dermatitis.
Tazarotene Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Vadivarhe Speciality Chemicals Limited | +91-9028832204 +91-9028832204 | Maharashtra, India | 38 | 58 | Inquiry |
| Laxai Life Sciences | +91-4023480125 +91-4023480125 | Hyderabad, India | 21 | 58 | Inquiry |
| BDR Pharmaceuticals International Pvt Ltd | +91-2240560560 +91-7718884418 | Maharashtra, India | 206 | 58 | Inquiry |
| PANCHSHEEL ORGANICS LTD | +91-9821053955 +91-9324201019 | Mumbai, India | 82 | 58 | Inquiry |
| Enaltec Labs Pvt Ltd | +91-9167119247 +91-9167119247 | Maharashtra, India | 49 | 58 | Inquiry |
| Maithri Drugs Pvt Ltd | +91-9059204566 +91-9848881740 | Telangana, India | 64 | 58 | Inquiry |
| Indo China Pharma Co., | +91 22 6534 0500 | Mumbai, India | 11 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
| GLENMARK LIFE SCIENCES LTD | +91 22 4018 9999 | New Delhi, India | 103 | 58 | Inquiry |
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