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ChemicalBook > Product Catalogue >Natural Products >Steroids >Tigogenin

Tigogenin

Tigogenin Structure
  • ₹0
  • Product name: Tigogenin
  • CAS: 77-60-1
  • MF: C27H44O3
  • MW: 416.64
  • EINECS:201-041-9
  • MDL Number:MFCD00067287
  • Synonyms:TIGOGENIN;(25r)-5-alpha-spirostan-3-beta-o ;25R,5ALPHA-SPIROSTAN-3BETA-OL;5-ALPHA, 20-ALPHA, 22-ALPHA, 25D-SPIROSTAN-3-BETA-OL;(25R)-5-Spirostan-3-ol ;(3-beta,5-alpha,25r)-spirostan-3-o ;5-alpha-spirostan-3-beta-ol ;5alpha-Spirostan-3beta-ol, (25R)-
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :202-204°C
alpha :-68 º (c=0.8g/100ml, CHCl3)
Boiling point :474.91°C (rough estimate)
Density :1.0362 (rough estimate)
refractive index :1.4700 (estimate)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly)
form :Solid
pka :15.14±0.70(Predicted)
color :Off-White
CAS DataBase Reference :77-60-1(CAS DataBase Reference)
NIST Chemistry Reference :Tigogenin(77-60-1)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Tigogenin is a steroidal sapogenin that has been found in A. sisalana and has diverse biological activities. It increases the proliferation rate of, as well as mRNA levels of genes encoding the osteoblastic differentiation markers Cbfa1, collagen type I, and osteocalcin in, mouse bone marrow stromal cells (BMSCs) in a concentration-dependent manner. It also increases matrix calcium deposition in BMSCs when used at concentrations of 30 and 90 μM. Tigogenin is active against the fungus A. fumigatus (MIC50 = 16 μg/ml). It inhibits carrageenan-induced paw edema in rats when administered at a dose of 4.2 μg/kg.

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Suppliers and manufacturers

career henan chemical co
Tigogenin
₹7.00 /1kg
Tigogenin CAS: 77-60-1
Amantech Chemicals Private Limited
Henan Tianfu Chemical Co.,Ltd.
Chengdu Biopurify Phytochemicals Ltd.
Chongqing Chemdad Co., Ltd
Neostar United (Changzhou) Industrial Co., Ltd.
Hubei Ipure Biology Co., Ltd
Hefei TNJ Chemical Industry Co.,Ltd.
ANHUI WITOP BIOTECH CO., LTD
changzhou huayang technology co., ltd