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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >Timosaponin A-III

Timosaponin A-III

Timosaponin A-III Structure
  • ₹0
  • Product name: Timosaponin A-III
  • CAS: 41059-79-4
  • MF: C39H64O13
  • MW: 740.92
  • EINECS:
  • MDL Number:MFCD01631164
  • Synonyms:[(25S)-5β-Spirostan-3β-yl]2-O-(β-D-glucopyranosyl)-β-D-galactopyranoside;Timosaponin A-III;TIMOSAPONIN A3 (SYN. TIMOSAPONIN A-III);TIMOSAPONIN A-3;TIMOSAPONIN A-;AnemarsaponinA3;Filiferin B;XilingsaponinA
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :317-322 °C
Boiling point :862.8±65.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml
form :White to off white solid.
pka :12.85±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Timosaponin A3 suppresses certain human tumor processes and has the potential to be developed as an anticancer agent. Reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. Induction of mitochondrial-dependent apoptosis in HepG2 human hepatocellular carcinoma cells.Timosaponin A3 is a potent inhibitor of U46619, that induces rat platelet aggregation and exhibited superior selectivity for the TP receptor vs. other G protein-coupled receptors and a PKC activator.

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Suppliers and manufacturers

career henan chemical co
Timosaponin A-III
₹3.00 /1KG
Timosaponin A-III CAS:41059-79-4
CHEMSWORTH
Chengdu Biopurify Phytochemicals Ltd.
BOC Sciences
Neostar United (Changzhou) Industrial Co., Ltd.
Hubei Ipure Biology Co., Ltd
Hefei TNJ Chemical Industry Co.,Ltd.
ANHUI WITOP BIOTECH CO., LTD
Dayang Chem (Hangzhou) Co.,Ltd.
Labnetwork lnc.