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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Sulfonamides and synergist >Trimethoprim

Trimethoprim

Trimethoprim Structure
  • ₹711 - ₹96836.4
  • Product name: Trimethoprim
  • CAS: 738-70-5
  • MF: C14H18N4O3
  • MW: 290.32
  • EINECS:212-006-2
  • MDL Number:MFCD00036761
  • Synonyms:TRIMETHOPRIMRESEARCH GRADE;TRIMETHOPRIMMICRONIZED;5-[(3,4,5-TriMethoxyphenyl)Methyl]-;TriMethopriM COS;TriMethopriM 0;TMP (triMethopriM);Trimethoprim solution,1000ppm;Trimethoprim Solution, 100ppm
16 prices
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Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)
  • SRL
  • ottokemi

Package

  • 100MG
  • 250MG
  • 1G
  • 5gm
  • 5G
  • 25gm
  • 25G
  • 100G
  • 500G
  • 5Gms
  • 25Gms
  • ManufacturerSigma-Aldrich(India)
  • Product number92131
  • Product descriptionTrimethoprim crystallized, ≥99.0% (HPLC)
  • Packaging1G
  • Price₹4394.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number46984
  • Product descriptionTrimethoprim VETRANAL?, analytical standard
  • Packaging250MG
  • Price₹6505.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1056
  • Product descriptionTrimethoprim Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8465.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number92131
  • Product descriptionTrimethoprim crystallized, ≥99.0% (HPLC)
  • Packaging5G
  • Price₹13390.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7883
  • Product descriptionTrimethoprim ≥98% (HPLC)
  • Packaging5G
  • Price₹14718.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number16967
  • Product descriptionTrimethoprim certified reference material, TraceCERT?
  • Packaging100MG
  • Price₹15393.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7883
  • Product descriptionTrimethoprim ≥98% (HPLC)
  • Packaging25G
  • Price₹31779.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number92131
  • Product descriptionTrimethoprim crystallized, ≥99.0% (HPLC)
  • Packaging25G
  • Price₹52544.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7883
  • Product descriptionTrimethoprim ≥98% (HPLC)
  • Packaging100G
  • Price₹96836.4
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT2286
  • Product descriptionTrimethoprim
  • Packaging25G
  • Price₹4800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT2286
  • Product descriptionTrimethoprim
  • Packaging100G
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT2286
  • Product descriptionTrimethoprim
  • Packaging500G
  • Price₹19500
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number18879
  • Product descriptionTrimethoprim (TMP), 98.5%
  • Packaging5Gms
  • Price₹750
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number18879
  • Product descriptionTrimethoprim (TMP), 98.5%
  • Packaging25Gms
  • Price₹2980
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number T 2200
  • Product descriptionTrimethoprim 98%
  • Packaging5gm
  • Price₹711
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number T 2200
  • Product descriptionTrimethoprim 98%
  • Packaging25gm
  • Price₹2808
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 92131 Trimethoprim crystallized, ≥99.0% (HPLC) 1G ₹4394.95 2022-06-14 Buy
Sigma-Aldrich(India) 46984 Trimethoprim VETRANAL?, analytical standard 250MG ₹6505.83 2022-06-14 Buy
Sigma-Aldrich(India) PHR1056 Trimethoprim Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8465.15 2022-06-14 Buy
Sigma-Aldrich(India) 92131 Trimethoprim crystallized, ≥99.0% (HPLC) 5G ₹13390.53 2022-06-14 Buy
Sigma-Aldrich(India) T7883 Trimethoprim ≥98% (HPLC) 5G ₹14718.6 2022-06-14 Buy
Sigma-Aldrich(India) 16967 Trimethoprim certified reference material, TraceCERT? 100MG ₹15393.15 2022-06-14 Buy
Sigma-Aldrich(India) T7883 Trimethoprim ≥98% (HPLC) 25G ₹31779.3 2022-06-14 Buy
Sigma-Aldrich(India) 92131 Trimethoprim crystallized, ≥99.0% (HPLC) 25G ₹52544.55 2022-06-14 Buy
Sigma-Aldrich(India) T7883 Trimethoprim ≥98% (HPLC) 100G ₹96836.4 2022-06-14 Buy
TCI Chemicals (India) T2286 Trimethoprim 25G ₹4800 2022-05-26 Buy
TCI Chemicals (India) T2286 Trimethoprim 100G ₹9800 2022-05-26 Buy
TCI Chemicals (India) T2286 Trimethoprim 500G ₹19500 2022-05-26 Buy
SRL 18879 Trimethoprim (TMP), 98.5% 5Gms ₹750 2022-05-26 Buy
SRL 18879 Trimethoprim (TMP), 98.5% 25Gms ₹2980 2022-05-26 Buy
ottokemi T 2200 Trimethoprim 98% 5gm ₹711 2022-05-26 Buy
ottokemi T 2200 Trimethoprim 98% 25gm ₹2808 2022-05-26 Buy

Properties

Melting point :199-203 °C
Boiling point :432.41°C (rough estimate)
Density :1.1648 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :white powder
pka :6.6(at 25℃)
color :colorless or white
Water Solubility :<0.1 g/100 mL at 24 ºC
Merck :14,9709
BRN :625127
BCS Class :2
Stability :Stable. Incompatible with strong oxidizing agents, acids.
CAS DataBase Reference :738-70-5(CAS DataBase Reference)
NIST Chemistry Reference :Trimethoprim(738-70-5)
EPA Substance Registry System :Trimethoprim (738-70-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Trimethoprim is a synthetic antibiotic that inhibits dihydrofolate reductase (DHFR), which is necessary for the synthesis of purines, amino acids, and thymidylic acid. Trimethoprim shows prominent selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively). Trimethoprim, commonly used in combination with sulfamethoxazole to minimize acquired resistance, has long been used against urinary tract infections. It may also have prophylactic applications, for example in patients receiving biologic agents during inflammation.

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