VARESPLADIB
- ₹11009.03 - ₹44339.2
- Product name: VARESPLADIB
- CAS: 172732-68-2
- MF: C21H20N2O5
- MW: 380.39
- EINECS:1592732-453-0
- MDL Number:MFCD00944812
- Synonyms:LY-333013;Varespladib (LY315920);2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid;2-(1-benzyl-2-ethyl-3-oxamoylindol-4-yl)oxyacetic acid;VARESPLADIB;LY315920(Varespladib);2-[[3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]Acetic Acid;[[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML1100
- Product descriptionVarespladib ≥98% (HPLC)
- Packaging5MG
- Price₹11009.03
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1100
- Product descriptionVarespladib ≥98% (HPLC)
- Packaging25MG
- Price₹44339.2
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML1100 | Varespladib ≥98% (HPLC) | 5MG | ₹11009.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML1100 | Varespladib ≥98% (HPLC) | 25MG | ₹44339.2 | 2022-06-14 | Buy |
Properties
Melting point :230-234 °C
Boiling point :667.9±65.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
pka :3.12±0.40(Predicted)
color :white to beige
Boiling point :667.9±65.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
pka :3.12±0.40(Predicted)
color :white to beige
Safety Information
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Description
LY315920 is an inhibitor of human group IIA (hGIIA) secretory phospholipase A2 (sPLA2; IC50 = 9 nM). It also potently inhibits human GIIE and GX isoforms, as well as the corresponding mouse isoforms, but poorly inhibits other PLA2 enzymes. LY315920 inhibits sPLA2-induced release of thromboxane A2 from isolated guinea pig lung bronchoalveolar lavage cells (IC50 = 0.79 μM). Intravenous or oral administration of LY315920 to transgenic mice expressing human sPLA2 inhibits serum sPLA2 activity in a dose-related manner over four hours.Related product price
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