Vinblastine sulfate
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- ₹4135.15 - ₹70676.43
- Product name: Vinblastine sulfate
- CAS: 143-67-9
- MF: C46H60N4O13S
- MW: 909.05
- EINECS:205-606-0
- MDL Number:MFCD00082457
- Synonyms:29060le ;nsc49842 ;rozevinsulfate ;velbe ;vincaleukoblastine,sulfate(1:1)(salt) ;Vinblastine, sulphate salt;VLB, Vincaleukoblastine sulphate salt;Vinblastine Sulphate USP
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- Sigma-Aldrich(India)
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- 1MG
- 5MG
- 10MG
- 25MG
- 50MG
- 100MG
- ManufacturerSigma-Aldrich(India)
- Product numberV1377
- Product descriptionVinblastine sulfate salt ≥97% (HPLC)
- Packaging1MG
- Price₹4135.15
- Updated2022-06-14
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- ManufacturerSigma-Aldrich(India)
- Product numberV1377
- Product descriptionVinblastine sulfate salt ≥97% (HPLC)
- Packaging5MG
- Price₹12784.33
- Updated2022-06-14
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- ManufacturerSigma-Aldrich(India)
- Product numberV1377
- Product descriptionVinblastine sulfate salt ≥97% (HPLC)
- Packaging10MG
- Price₹20740.7
- Updated2022-06-14
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- ManufacturerSigma-Aldrich(India)
- Product numberPHR2698
- Product descriptionVinblastine Sulfate certified reference material, pharmaceutical secondary standard
- Packaging100MG
- Price₹33568.33
- Updated2022-06-14
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- ManufacturerSigma-Aldrich(India)
- Product numberV1377
- Product descriptionVinblastine sulfate salt ≥97% (HPLC)
- Packaging25MG
- Price₹46515.03
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberV1377
- Product descriptionVinblastine sulfate salt ≥97% (HPLC)
- Packaging50MG
- Price₹70676.43
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | V1377 | Vinblastine sulfate salt ≥97% (HPLC) | 1MG | ₹4135.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | V1377 | Vinblastine sulfate salt ≥97% (HPLC) | 5MG | ₹12784.33 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | V1377 | Vinblastine sulfate salt ≥97% (HPLC) | 10MG | ₹20740.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR2698 | Vinblastine Sulfate certified reference material, pharmaceutical secondary standard | 100MG | ₹33568.33 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | V1377 | Vinblastine sulfate salt ≥97% (HPLC) | 25MG | ₹46515.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | V1377 | Vinblastine sulfate salt ≥97% (HPLC) | 50MG | ₹70676.43 | 2022-06-14 | Buy |
Properties
Melting point :267 °C (dec.)(lit.)
alpha :-21.7 º (c=2, CH3OH 21 ºC)
storage temp. :2-8°C
solubility :H2O: 10 mg/mL
form :powder
color :white
PH :3.5~5.0 (1g/l, 25℃)
Water Solubility :>=1 g/100 mL at 24.5 ºC
Merck :13,10044
BRN :3659812
InChIKey :KDQAABAKXDWYSZ-PNYVAJAMSA-N
CAS DataBase Reference :143-67-9(CAS DataBase Reference)
IARC :3 (Vol. 26, Sup 7) 1987
EPA Substance Registry System :Vinblastine sulfate (143-67-9)
alpha :-21.7 º (c=2, CH3OH 21 ºC)
storage temp. :2-8°C
solubility :H2O: 10 mg/mL
form :powder
color :white
PH :3.5~5.0 (1g/l, 25℃)
Water Solubility :>=1 g/100 mL at 24.5 ºC
Merck :13,10044
BRN :3659812
InChIKey :KDQAABAKXDWYSZ-PNYVAJAMSA-N
CAS DataBase Reference :143-67-9(CAS DataBase Reference)
IARC :3 (Vol. 26, Sup 7) 1987
EPA Substance Registry System :Vinblastine sulfate (143-67-9)
Safety Information
Symbol(GHS): |
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Description
Vinblastine, derived from C. roseus, also known as V. rosea, a Madagascar periwinkle, is an antimicrotubule drug used to treat certain cancers, including Hodgkin’s lymphoma, non-small cell lung, breast, head and neck, and testicular cancer. Like its chemical analog vincristine, vinblastine binds tubulin, inhibiting the assembly of microtubules and causing M phase-specific cell cycle arrest by disrupting microtubule assembly and proper formation of the mitotic spindle. It has been shown to inhibit steady-state tubulin addition to microtubules with a Ki value of 0.18 μM, inhibit B16 melanoma cell proliferation with an IC50 value of 1 nM, and produce complete inhibition of L-cell proliferation at 40 nM. Vinblastine is reported to be an effective component of certain chemotherapy regimens, particularly when used with bleomycin and methotrexate in vinblastine, bleomycin, and methotrexate combination chemotherapy for Stage IA or IIA Hodgkin lymphomas.More related product prices
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