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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Natural sources of antineoplastic >Vincristine sulfate

Vincristine sulfate

Vincristine sulfate Structure
  • ₹11734.3 - ₹118089.93
  • Product name: Vincristine sulfate
  • CAS: 2068-78-2
  • MF: C46H58N4O14S
  • MW: 923.04
  • EINECS:218-190-0
  • MDL Number:MFCD08706469
  • Synonyms:VINCRISTINE SULFATE;VINCRISTINE SULFATE, APOCYNACEAE SPECIES;VCR, LEUKOCRISTINE SULFATE;VCR SULFATE;Vincristine,Leurocristine,Oncovin,Vinblastine;Vincristin Sulfate;Vincristine sulfate,95%;Vincaleukoblastine, 22-oxo-, sulfate (1:1)
7 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberV8388
  • Product descriptionVincristine sulfate meets USP testing specifications
  • Packaging1MG
  • Price₹11734.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberV8879
  • Product descriptionVincristine sulfate salt 95.0-105.0% (HPLC), powder or crystals
  • Packaging1MG
  • Price₹12037.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberV8879
  • Product descriptionVincristine sulfate salt 95.0-105.0% (HPLC), powder or crystals
  • Packaging5MG
  • Price₹13953.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberV8388
  • Product descriptionVincristine sulfate meets USP testing specifications
  • Packaging5MG
  • Price₹30602.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number677181
  • Product descriptionVincristine Sulfate, Apocynaceae sp. - CAS 2068-78-2 - Calbiochem Indole alkaloid that binds to tubulin, inhibiting formation of microtubules.
  • Packaging10MG
  • Price₹56840
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberV8879
  • Product descriptionVincristine sulfate salt 95.0-105.0% (HPLC), powder or crystals
  • Packaging25MG
  • Price₹56874.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberV8388
  • Product descriptionVincristine sulfate meets USP testing specifications
  • Packaging25MG
  • Price₹118089.93
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) V8388 Vincristine sulfate meets USP testing specifications 1MG ₹11734.3 2022-06-14 Buy
Sigma-Aldrich(India) V8879 Vincristine sulfate salt 95.0-105.0% (HPLC), powder or crystals 1MG ₹12037.4 2022-06-14 Buy
Sigma-Aldrich(India) V8879 Vincristine sulfate salt 95.0-105.0% (HPLC), powder or crystals 5MG ₹13953.43 2022-06-14 Buy
Sigma-Aldrich(India) V8388 Vincristine sulfate meets USP testing specifications 5MG ₹30602.28 2022-06-14 Buy
Sigma-Aldrich(India) 677181 Vincristine Sulfate, Apocynaceae sp. - CAS 2068-78-2 - Calbiochem Indole alkaloid that binds to tubulin, inhibiting formation of microtubules. 10MG ₹56840 2022-06-14 Buy
Sigma-Aldrich(India) V8879 Vincristine sulfate salt 95.0-105.0% (HPLC), powder or crystals 25MG ₹56874.55 2022-06-14 Buy
Sigma-Aldrich(India) V8388 Vincristine sulfate meets USP testing specifications 25MG ₹118089.93 2022-06-14 Buy

Properties

Melting point :300 °C
Boiling point :273-281 °C
alpha :D26 +8.5° (c = 0.8)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :methanol: soluble20mg/mL
form :lyophilized powder
color :white to off-white
Water Solubility :>=1 g/100 mL at 24 ºC
BRN :3924631
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
InChIKey :AQTQHPDCURKLKT-HSMPTBRCNA-N
IARC :3 (Vol. 26, Sup 7) 1987
EPA Substance Registry System :Vincristine sulfate (2068-78-2)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.

Description

Vincristine is an antimitotic vinca alkaloid, isolated from the plant V. rosea. It irreversibly blocks mitosis by binding to tubulin (Ki = 85 nM) and inhibiting tubulin polymerization. Vincristine is exported from cells via the ATP-binding cassette transporter P-glycoprotein, but not by multidrug resistance-associated protein. Its effectiveness in blocking the proliferation of cancer cells is affected by overexpression of P-glycoprotein.

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