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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antiepileptic and anticonvulsant >Zonisamide

Zonisamide

Zonisamide Structure
  • ₹3200 - ₹13326.6
  • Product name: Zonisamide
  • CAS: 68291-97-4
  • MF: C8H8N2O3S
  • MW: 212.23
  • EINECS:614-395-8
  • MDL Number:MFCD00865316
  • Synonyms:BENZO[D]ISOXAZOL-3-YL-METHANESULFONAMIDE;1,2-BENZISOXAZOLE-3-METHANESULFONAMIDE;ZON;ZONISAMIDE;3-(sulfamoylmethyl)-1,2-benzisoxazole ;ad-810 ;ci-912 ;exceglan
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 200MG
  • 1ML
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberZ0026
  • Product descriptionZonisamide
  • Packaging200MG
  • Price₹3200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberZ0026
  • Product descriptionZonisamide
  • Packaging1G
  • Price₹9000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.08508
  • Product descriptionZonisamide - CAS 68291-97-4 - Calbiochem An antiepileptic agent that blocks voltage-dependent Na(+) channels and T-type Ca(2+) channels.
  • Packaging10MG
  • Price₹12330
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberZ-005
  • Product descriptionZonisamide solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹13326.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) Z0026 Zonisamide 200MG ₹3200 2022-05-26 Buy
TCI Chemicals (India) Z0026 Zonisamide 1G ₹9000 2022-05-26 Buy
Sigma-Aldrich(India) 5.08508 Zonisamide - CAS 68291-97-4 - Calbiochem An antiepileptic agent that blocks voltage-dependent Na(+) channels and T-type Ca(2+) channels. 10MG ₹12330 2022-06-14 Buy
Sigma-Aldrich(India) Z-005 Zonisamide solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹13326.6 2022-06-14 Buy

Properties

Melting point :275°C dec.
Boiling point :223°C (rough estimate)
Density :1.4306 (rough estimate)
refractive index :1.5690 (estimate)
Flash point :9℃
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :H2O: >5 mg/mL, soluble
form :solid
pka :10.2(at 25℃)
color :off-white
Merck :14,10192
InChIKey :UBQNRHZMVUUOMG-UHFFFAOYSA-N
CAS DataBase Reference :68291-97-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Zonisamide is a new generation of sulfonamide anticonvulsant that is primarily used as supplemental therapy in treatment of partial seizures in combination with other antiepileptic medications. Besides, it is approved to be applied as an adjunctive therapy in adults suffering from infantile spasm, mixed seizure types of Lennox–Gastaut syndrome, myoclonic, and generalized tonic clonic seizure. Recent studies have proved that zonisamide can acts as a migraine preventative medication and is effective in several cases of neuropathic pain. In an open-label trial, zonisamide shows positive effects on attenuating the symptoms of tardive dyskinesia.
It is assumed that zonisamide functions on the sodium and calcium channels in the brain cells, in which it controls electric-currents that are responsible for seizure activity. The FDA approved zonisamide in March 2000.

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