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ChemicalBook > Product Catalogue >API >Antibiotics >Agricultural antibiotics >Actidione

Actidione

Actidione Structure
  • ₹405 - ₹2623633.6
  • Product name: Actidione
  • CAS: 66-81-9
  • MF: C15H23NO4
  • MW: 281.35
  • EINECS:200-636-0
  • MDL Number:MFCD06202064
  • Synonyms:Cycloheximide Solution 100ug/ml in Acetonitrile;CYCLOHEXIMIDE READY MADE;4-[(2R)-2-[(1S,3S,5S)-3,5-DiMethyl-2-oxocyclohexyl]-2-hydroxyethyl]-2,6-piperidinedione;FT 3422-2;NaraMycin Microcapsule D 80;NaraMycin NM-MCU 80;β-[2-(3,5-DiMethyl-2-oxocyclohexyl)- 2-hydroxyethyl]glutariMide;980U/MG
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  • Sigma-Aldrich(India)
  • SRL
  • ottokemi

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  • 500mg
  • 1gm
  • 5gm
  • 1Gms
  • 5Gms
  • 100MG
  • 1ML
  • 5G
  • 1G
  • 239763-1KG
  • ManufacturerSigma-Aldrich(India)
  • Product number239764
  • Product descriptionCycloheximide, High Purity - CAS 66-81-9 - Calbiochem Antifungal antibiotic that inhibits protein synthesis in eukaryotes but not in prokaryotes.
  • Packaging100MG
  • Price₹6170
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number46401
  • Product descriptionCycloheximide PESTANAL?, analytical standard
  • Packaging100MG
  • Price₹6332.63
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number239765
  • Product descriptionInSolution Cycloheximide - CAS 66-81-9 - Calbiochem InSolution Cycloheximide, CAS 66-81-9, is a 100 mg/ml, sterile-filtered solution of Cycloheximide (Cat. No. 239763) in DMSO. An antifungal antibiotic
  • Packaging1ML
  • Price₹9490
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberC7698
  • Product descriptionCycloheximide from microbial, ≥94% (TLC)
  • Packaging1G
  • Price₹9504.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC4859
  • Product descriptionCycloheximide solution Ready-Made Solution, microbial, 100?mg/mL in DMSO, Suitable for cell culture
  • Packaging1ML
  • Price₹10812.9
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number01810
  • Product descriptionCycloheximide ≥95% (HPLC)
  • Packaging1G
  • Price₹11290.48
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberC1988
  • Product descriptionCycloheximide Biotechnology Performance Certified
  • Packaging5G
  • Price₹38080
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number239763-M
  • Product descriptionCycloheximide - CAS 66-81-9 - Calbiochem Cycloheximide, CAS 66-81-9, is an antifungal antibiotic that inhibits protein synthesis in eukaryotes but not prokaryotes.
  • Packaging239763-1KG
  • Price₹2623633.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number239763-M
  • Product descriptionCycloheximide - CAS 66-81-9 - Calbiochem Cycloheximide, CAS 66-81-9, is an antifungal antibiotic that inhibits protein synthesis in eukaryotes but not prokaryotes.
  • Packaging1G
  • Price₹12400
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1988
  • Product descriptionCycloheximide Biotechnology Performance Certified
  • Packaging1G
  • Price₹13520.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC7698
  • Product descriptionCycloheximide from microbial, ≥94% (TLC)
  • Packaging5G
  • Price₹22407.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number239764
  • Product descriptionCycloheximide, High Purity - CAS 66-81-9 - Calbiochem Antifungal antibiotic that inhibits protein synthesis in eukaryotes but not in prokaryotes.
  • Packaging1G
  • Price₹22650
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number01810
  • Product descriptionCycloheximide ≥95% (HPLC)
  • Packaging5G
  • Price₹25925.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number239763-M
  • Product descriptionCycloheximide - CAS 66-81-9 - Calbiochem Cycloheximide, CAS 66-81-9, is an antifungal antibiotic that inhibits protein synthesis in eukaryotes but not prokaryotes.
  • Packaging5G
  • Price₹34420.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number86620
  • Product descriptionCycloheximide extrapure, 94%
  • Packaging100mg
  • Price₹440
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number95581
  • Product descriptionCycloheximide for tissue culture, 94%
  • Packaging100mg
  • Price₹720
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 239764 Cycloheximide, High Purity - CAS 66-81-9 - Calbiochem Antifungal antibiotic that inhibits protein synthesis in eukaryotes but not in prokaryotes. 100MG ₹6170 2022-06-14 Buy
Sigma-Aldrich(India) 46401 Cycloheximide PESTANAL?, analytical standard 100MG ₹6332.63 2022-06-14 Buy
Sigma-Aldrich(India) 239765 InSolution Cycloheximide - CAS 66-81-9 - Calbiochem InSolution Cycloheximide, CAS 66-81-9, is a 100 mg/ml, sterile-filtered solution of Cycloheximide (Cat. No. 239763) in DMSO. An antifungal antibiotic 1ML ₹9490 2022-06-14 Buy
Sigma-Aldrich(India) C7698 Cycloheximide from microbial, ≥94% (TLC) 1G ₹9504.35 2022-06-14 Buy
Sigma-Aldrich(India) C4859 Cycloheximide solution Ready-Made Solution, microbial, 100?mg/mL in DMSO, Suitable for cell culture 1ML ₹10812.9 2022-06-14 Buy
Sigma-Aldrich(India) 01810 Cycloheximide ≥95% (HPLC) 1G ₹11290.48 2022-06-14 Buy
Sigma-Aldrich(India) C1988 Cycloheximide Biotechnology Performance Certified 5G ₹38080 2022-06-14 Buy
Sigma-Aldrich(India) 239763-M Cycloheximide - CAS 66-81-9 - Calbiochem Cycloheximide, CAS 66-81-9, is an antifungal antibiotic that inhibits protein synthesis in eukaryotes but not prokaryotes. 239763-1KG ₹2623633.6 2022-06-14 Buy
Sigma-Aldrich(India) 239763-M Cycloheximide - CAS 66-81-9 - Calbiochem Cycloheximide, CAS 66-81-9, is an antifungal antibiotic that inhibits protein synthesis in eukaryotes but not prokaryotes. 1G ₹12400 2022-06-14 Buy
Sigma-Aldrich(India) C1988 Cycloheximide Biotechnology Performance Certified 1G ₹13520.43 2022-06-14 Buy
Sigma-Aldrich(India) C7698 Cycloheximide from microbial, ≥94% (TLC) 5G ₹22407.75 2022-06-14 Buy
Sigma-Aldrich(India) 239764 Cycloheximide, High Purity - CAS 66-81-9 - Calbiochem Antifungal antibiotic that inhibits protein synthesis in eukaryotes but not in prokaryotes. 1G ₹22650 2022-06-14 Buy
Sigma-Aldrich(India) 01810 Cycloheximide ≥95% (HPLC) 5G ₹25925.88 2022-06-14 Buy
Sigma-Aldrich(India) 239763-M Cycloheximide - CAS 66-81-9 - Calbiochem Cycloheximide, CAS 66-81-9, is an antifungal antibiotic that inhibits protein synthesis in eukaryotes but not prokaryotes. 5G ₹34420.01 2022-06-14 Buy
SRL 86620 Cycloheximide extrapure, 94% 100mg ₹440 2022-05-26 Buy
SRL 95581 Cycloheximide for tissue culture, 94% 100mg ₹720 2022-05-26 Buy

Properties

Melting point :111-116 °C
alpha :-28.5 º (c=1, CHCl3)
Boiling point :492℃
Density :1.0867 (rough estimate)
refractive index :1.5000 (estimate)
Flash point :87°0°(230°F)
storage temp. :2-8°C
solubility :Soluble in Ethanol (up to 14 mg/ml) or in Water (up to 7 mg/ml).
pka :11.61±0.40(Predicted)
form :Glassy Irregular Shaped Granules
color :White
Water Solubility :2.1 g/100 mL (2 ºC)
BRN :88868
Stability :Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, alkali.
CAS DataBase Reference :66-81-9(CAS DataBase Reference)
EPA Substance Registry System :Cycloheximide (66-81-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Cycloheximide is a glutarimide antibiotic produced by S. griseus that inhibits protein synthesis in eukaryotes (IC50 = 5-50 μM) by interfering with translational elongation. Its effects on protein synthesis can either induce or inhibit apoptosis depending on cell type. Cycloheximide is widely used as a tool in molecular biology research for ribosome profiling and translational profiling as well as to determine the half-life of a protein.

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