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Amoxapine

Amoxapine Structure
  • ₹4708.88 - ₹87801.58
  • Product name: Amoxapine
  • CAS: 14028-44-5
  • MF: C17H16ClN3O
  • MW: 313.78
  • EINECS:237-867-1
  • MDL Number:MFCD00069210
  • Synonyms:Moxadil;AMOXAPINE;2-CHLORO-11-(1-PIPERAZINYL)DIBENZ(B,F)(1,4)OXAZEPINE;AMOXAPINE TRICYCLIC ANTIDEPRESS;Defanyl;8-Chloro-6-piperazin-1-ylbenzo[b][1,5]benzoxazepine;ENC2378671;2-Chloro-11-(1-piperazinyl)dibenzo[b,f][1,4]
5 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberA2499
  • Product descriptionAmoxapine min. 97.0 %
  • Packaging1G
  • Price₹6200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA129
  • Product descriptionAmoxapine
  • Packaging100MG
  • Price₹4708.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA129
  • Product descriptionAmoxapine
  • Packaging500MG
  • Price₹14635.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1841
  • Product descriptionAmoxapine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹23739.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA129
  • Product descriptionAmoxapine
  • Packaging5G
  • Price₹87801.58
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2499 Amoxapine min. 97.0 % 1G ₹6200 2022-05-26 Buy
Sigma-Aldrich(India) A129 Amoxapine 100MG ₹4708.88 2022-06-14 Buy
Sigma-Aldrich(India) A129 Amoxapine 500MG ₹14635.4 2022-06-14 Buy
Sigma-Aldrich(India) PHR1841 Amoxapine Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹23739.23 2022-06-14 Buy
Sigma-Aldrich(India) A129 Amoxapine 5G ₹87801.58 2022-06-14 Buy

Properties

Melting point :175-1760C
Boiling point :469.9±55.0 °C(Predicted)
Density :1.2613 (rough estimate)
refractive index :1.5800 (estimate)
Flash point :9℃
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :methanol: soluble
form :Solid
pka :pKa 7.6 (Uncertain)
color :Crystals from benzene/pet ether
Merck :14,576
Stability :Stable under recommended storage conditions., Stable Under Recommended Storage C
CAS DataBase Reference :14028-44-5(CAS DataBase Reference)
NIST Chemistry Reference :Amoxapine(14028-44-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Amoxapine is a tetracyclic antidepressant with a wide range of pharmacological effects. It inhibits norepinephrine and serotonin reuptake, binding the respective transporters with Kd values of 16 and 58 nM. It has also been shown to act as either an antagonist or inverse agonist at serotonin 5-HT2A, 2B, 2C, 3, 6, 7 (Kis = 1 and 2 nM for 5-HT2A and 5-HT2C, respectively), dopamine D2, 3, 4 (Kd = 160 nM for D2), α1-adrenergic (Kd = 50 nM), and histamine H1 (Kd = 25 nM) receptors.

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