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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antidepressants, Antimanics drugs >Trazodone

Trazodone

Trazodone Structure
  • ₹0
  • Product name: Trazodone
  • CAS: 19794-93-5
  • MF: C19H22ClN5O
  • MW: 371.86
  • EINECS:243-317-1
  • MDL Number:MFCD00242886
  • Synonyms:8-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-6,8,9-triazabicyclo[4.3.0]nona-2,4,9-trien-7-one;desyrel;Trazodone Hydrochloride 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-1,2,4-tri;trazon;TRAZODONE;trialodine;Trazodone (base and/or unspecified salts);2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :86-870C
Boiling point :528.5±60.0 °C(Predicted)
Density :1.3141 (rough estimate)
refractive index :1.5790 (estimate)
storage temp. :Store at -20°C
solubility :DMSO: 45 mg/mL (121.01 mM);Ethanol: 17 mg/mL (45.72 mM)
form :Solid
pka :pKa (50% ethanol): 6.14(at 25℃)
color :White to off-white
Water Solubility :Water: Insoluble
BCS Class :1
CAS DataBase Reference :19794-93-5(CAS DataBase Reference)
NIST Chemistry Reference :Desyrel(trazodone hcl salt)(19794-93-5)
EPA Substance Registry System :1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]- (19794-93-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

It is believed that trazodone, in therapeutic doses, inhibits the neuronal reuptake of serotonin. It is not a MAO inhibitor or a CNS stimulator. It has a minor influence on the reuptake of norepinephrine and dopamine. In addition, it does not bind with cholinergic or α-adrenergic receptors.

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