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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antiepileptic and anticonvulsant >Gabapentin

Gabapentin

Gabapentin Structure
  • ₹6596.8 - ₹66876.85
  • Product name: Gabapentin
  • CAS: 60142-96-3
  • MF: C9H17NO2
  • MW: 171.24
  • EINECS:262-076-3
  • MDL Number:MFCD00865286
  • Synonyms:GABAPENTIN;GOE-3450;(1-AMINOMETHYL-CYCLOHEXYL)-ACETIC ACID;AKOS 92109;1-(Aminomethyl)-cyclohexaneacetic acid, Neurontin;Goe-3450:GOE-3450:Neurontin;1-(Aminomethyl)cyclohexane-1-acetic acid;Gabapentin (250 mg)G0E0050.999mg/mg(ai)
7 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • 1ML
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberG0318
  • Product descriptionGabapentin min. 98.0 %
  • Packaging5G
  • Price₹7700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberG0318
  • Product descriptionGabapentin min. 98.0 %
  • Packaging25G
  • Price₹23300
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG-007
  • Product descriptionGabapentin solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹6596.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1049
  • Product descriptionGabapentin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹10002.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.08506
  • Product descriptionGabapentin - CAS 60142-96-3 - Calbiochem A water soluble GABA analog that interacts with voltage-gated calcium channels in cortical neurons.
  • Packaging10MG
  • Price₹12940
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG154
  • Product descriptionGabapentin solid
  • Packaging10MG
  • Price₹13975.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG154
  • Product descriptionGabapentin solid
  • Packaging50MG
  • Price₹66876.85
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) G0318 Gabapentin min. 98.0 % 5G ₹7700 2022-05-26 Buy
TCI Chemicals (India) G0318 Gabapentin min. 98.0 % 25G ₹23300 2022-05-26 Buy
Sigma-Aldrich(India) G-007 Gabapentin solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹6596.8 2022-06-14 Buy
Sigma-Aldrich(India) PHR1049 Gabapentin Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹10002.3 2022-06-14 Buy
Sigma-Aldrich(India) 5.08506 Gabapentin - CAS 60142-96-3 - Calbiochem A water soluble GABA analog that interacts with voltage-gated calcium channels in cortical neurons. 10MG ₹12940 2022-06-14 Buy
Sigma-Aldrich(India) G154 Gabapentin solid 10MG ₹13975.08 2022-06-14 Buy
Sigma-Aldrich(India) G154 Gabapentin solid 50MG ₹66876.85 2022-06-14 Buy

Properties

Melting point :162°C
Boiling point :314.4±15.0 °C(Predicted)
Density :1.058±0.06 g/cm3(Predicted)
Flash point :9℃
storage temp. :2-8°C
solubility :H2O: 10 mg/mL
form :solid
pka :pKa1 (25°) 3.68; pKa2 10.70
color :off-white
Merck :14,4319
BRN :2359739
BCS Class :3
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
InChIKey :UGJMXCAKCUNAIE-UHFFFAOYSA-N
CAS DataBase Reference :60142-96-3(CAS DataBase Reference)
EPA Substance Registry System :Cyclohexaneacetic acid, 1-(aminomethyl)- (60142-96-3)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P311 Call a POISON CENTER or doctor/physician.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.

Description

Gabapentin was introduced in 1993 in the UK and early 1994 in the USA as an adjunctive therapy in the treatment of refractory partial seizures and secondarily generalized tonic-clonic seizures. Although being a lipophilic analog of the neurotransmitter GABA, gabapentin appears to exert its anticonvulsive function by a GABA receptor independent mechanism, possibly involving the L-system amino acid transporter protein. Gabapentin easily crosses the blood brain barrier and exhibits a favorable pharmacokinetic profile with high tolerability. It does not interfere with the metabolism of other concomitant administered antiepileptic drugs, thus having a low potential for drug interactions. Studies are currently underway for the use of gabapentin as mono-therapy for the treatment of various seizures.

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