Apafant
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- ₹15869.45 - ₹63964.93
- Product name: Apafant
- CAS: 105219-56-5
- MF: C22H22ClN5O2S
- MW: 455.96
- EINECS:
- MDL Number:MFCD00865271
- Synonyms:4-[3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-oxopropyl]-morpholine;WEB 208;WEB 2086BS;4-[3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-α][1,4]diazepin-2-yl]-1-oxopropyl]-morpholine;3-[4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-1-(4-morpholinyl)-1-propanone;4-(2-Chlorophenyl)-9-methyl-2-(3-morpholino-3-oxopropyl)-6H-thieno[3,2- f] [1,2,4]triazolo[4,3-a][1,4]diazepine;4-[3-[4[(2-CHLOROPHENYL)-9-METHYL-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A]DIAZEPIN-2-YL]-1-OXOPROPYL]]MORPHOLINE;WEB 2086
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0238
- Product descriptionWEB2086 ≥98% (HPLC)
- Packaging5MG
- Price₹15869.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0238
- Product descriptionWEB2086 ≥98% (HPLC)
- Packaging25MG
- Price₹63964.93
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0238 | WEB2086 ≥98% (HPLC) | 5MG | ₹15869.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0238 | WEB2086 ≥98% (HPLC) | 25MG | ₹63964.93 | 2022-06-14 | Buy |
Properties
Melting point :186-188°C
Boiling point :720.2±70.0 °C(Predicted)
Density :1.48
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :2.36±0.40(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :720.2±70.0 °C(Predicted)
Density :1.48
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :2.36±0.40(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Platelet-activating factor (PAF) is a biologically active phospholipid that activates platelets, polymorphonuclear leukocytes, monocytes, and macrophages. PAF also increases vascular permeability, decreases cardiac output, induces hypotension, stimulates uterine contraction, and has been implicated in pathological processes, such as inflammation and allergy. Apafant is a water soluble, selective PAF receptor antagonist that inhibits PAF binding to human PAF receptors with a Ki value of 9.9 nM. Apafant displays anti-inflammatory, antiangiogenic, and anticancer activity.More related product prices
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