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azd4635

azd4635 Structure
  • ₹0
  • Product name: azd4635
  • CAS: 1321514-06-0
  • MF: C15H11ClFN5
  • MW: 315.73
  • EINECS:
  • MDL Number:MFCD31618022
  • Synonyms:azd4635;HTL-1071;CPD1545;6-(2-chloro-6-methylpyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine;1,2,4-Triazin-3-amine, 6-(2-chloro-6-methyl-4-pyridinyl)-5-(4-fluorophenyl)-;AZD-4635; HTL-1071;AZD-4635; AZD 4635; AZD4635; HTL-1071; HTL 1071; HTL1071;CS-2744
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :491.5±55.0 °C(Predicted)
Density :1.387±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:56.65(Max Conc. mg/mL);179.42(Max Conc. mM)
DMSO:PBS(pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.79(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);95.01(Max Conc. mM) form :A crystalline solid
pka :1.75±0.63(Predicted)
color :Off-white to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

AZD4635, is a novel adenosine 2A receptor (A2AR) inhibitor with a Ki of 1.7 nM.

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