Baclofen
- ₹3300 - ₹55023.48
- Product name: Baclofen
- CAS: 1134-47-0
- MF: C10H12ClNO2
- MW: 213.66
- EINECS:214-486-9
- MDL Number:MFCD00055143
- Synonyms:4-Amino-3-(p-chlorophenyl)butyric acid;Benzenepropanoic acid, β-(aminomethyl)-4-chloro-;CIBA Ba 34647;DL-4-Amino-3-p-chlorophenylbutanoic acid;DL-Baclofen;Hydrocinnamic acid, β-(aminomethyl)-p-chloro- (7CI, 8CI);β-(4-Chlorophenyl)-γ-aminobutyric acid;β-p-Chlorophenyl-GABA
7 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
Package
- 500MG
- 1G
- 5G
- 10G
- 25G
- ManufacturerSigma-Aldrich(India)
- Product numberB5399
- Product description(±)-Baclofen ≥98% (TLC), solid
- Packaging500MG
- Price₹5639.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1682
- Product descriptionBaclofen Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹13520.43
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberB5399
- Product description(±)-Baclofen ≥98% (TLC), solid
- Packaging5G
- Price₹30429.08
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberB5399
- Product description(±)-Baclofen ≥98% (TLC), solid
- Packaging10G
- Price₹55023.48
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberB3343
- Product descriptionBaclofen
- Packaging25G
- Price₹13800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberB3343
- Product descriptionBaclofen
- Packaging5G
- Price₹12600
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberB3343
- Product descriptionBaclofen
- Packaging1G
- Price₹3300
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | B5399 | (±)-Baclofen ≥98% (TLC), solid | 500MG | ₹5639.83 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1682 | Baclofen Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹13520.43 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | B5399 | (±)-Baclofen ≥98% (TLC), solid | 5G | ₹30429.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | B5399 | (±)-Baclofen ≥98% (TLC), solid | 10G | ₹55023.48 | 2022-06-14 | Buy |
TCI Chemicals (India) | B3343 | Baclofen | 25G | ₹13800 | 2022-05-26 | Buy |
TCI Chemicals (India) | B3343 | Baclofen | 5G | ₹12600 | 2022-05-26 | Buy |
TCI Chemicals (India) | B3343 | Baclofen | 1G | ₹3300 | 2022-05-26 | Buy |
Properties
Melting point :208-210°C
Boiling point :364.3±32.0 °C(Predicted)
Density :1.2069 (rough estimate)
refractive index :1.5500 (estimate)
storage temp. :2-8°C
solubility :1 M HCl: 50 mg/mL
form :solid
pka :pKa 3.87±0.1(H2O) (Uncertain)
color :white to very faintly yellow
Water Solubility :Soluble in dilute NaOH or dilute HCl. Soluble in water at approximately 4mg/ml at pH 7.6
Merck :14,937
Stability :Hygroscopic
InChI :InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
InChIKey :KPYSYYIEGFHWSV-UHFFFAOYSA-N
SMILES :C1(C=CC(Cl)=CC=1)C(CN)CC(=O)O
CAS DataBase Reference :1134-47-0(CAS DataBase Reference)
NIST Chemistry Reference :Baclofen(1134-47-0)
EPA Substance Registry System :.beta.-(Aminomethyl)-4-chlorobenzenepropanoic acid (1134-47-0)
Boiling point :364.3±32.0 °C(Predicted)
Density :1.2069 (rough estimate)
refractive index :1.5500 (estimate)
storage temp. :2-8°C
solubility :1 M HCl: 50 mg/mL
form :solid
pka :pKa 3.87±0.1(H2O) (Uncertain)
color :white to very faintly yellow
Water Solubility :Soluble in dilute NaOH or dilute HCl. Soluble in water at approximately 4mg/ml at pH 7.6
Merck :14,937
Stability :Hygroscopic
InChI :InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
InChIKey :KPYSYYIEGFHWSV-UHFFFAOYSA-N
SMILES :C1(C=CC(Cl)=CC=1)C(CN)CC(=O)O
CAS DataBase Reference :1134-47-0(CAS DataBase Reference)
NIST Chemistry Reference :Baclofen(1134-47-0)
EPA Substance Registry System :.beta.-(Aminomethyl)-4-chlorobenzenepropanoic acid (1134-47-0)
Safety Information
Symbol(GHS): | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Danger | ||||||||||||||
Hazard statements: |
|
||||||||||||||
Precautionary statements: |
|
Description
γ-Aminobutyric acid (GABA) is an inhibitory neurotransmitter that acts through heteromeric ligand-gated ion channels, GABAA and GABAC, and a G protein-coupled receptor, GABAB. (±)-Baclofen is a selective agonist of GABAB (IC50 = 200 nM). By activating GABAB, (±)-baclofen causes skeletal muscle relaxation and blocks spasticity. It also modifies animal responses to alcohol and cocaine.More related product prices
4-Aminobutyric acid 4-Phenylbutyric acid tert-Butylchlorodiphenylsilane Triphenylmethyl chloride 69308-37-8 S(+)-Baclofen BaclofenRelated product price
- 4-Aminobutyric acid
₹198-22245.38 - 4-Phenylbutyric acid
₹2423-27333 - CHLOROMETHYL BUTYRATE
₹7300