Brimonidine Tartrate
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- ₹20643.28
- Product name: Brimonidine Tartrate
- CAS: 70359-46-5
- MF: C15H16BrN5O6
- MW: 442.22
- EINECS:629-848-5
- MDL Number:MFCD07773072
- Synonyms:5-BROMO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-QUINOXALINAMINE TARTRATE;5-BROMO-6-(2-IMIDAZOLIN-2-YLAMINO)QUINOXALINE TARTRATE;BRIMONIDINE D-TARTRATE;BRIMONIDINE TARTATE;UK 14,304 TARTRATE;Brimonidine-L-Tartrate;Brimonidinne tartrate;Brimonidine Tartrate(Alphagan)
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 500MG
- ManufacturerSigma-Aldrich(India)
- Product numberPHR2795
- Product descriptionBrimonidine Tartrate pharmaceutical secondary standard, certified reference material
- Packaging500MG
- Price₹20643.28
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR2795 | Brimonidine Tartrate pharmaceutical secondary standard, certified reference material | 500MG | ₹20643.28 | 2022-06-14 | Buy |
Properties
Melting point :207-208°C (dec.)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: 1 mg/ml; PBS (pH 7.2): 3 mg/ml
form :Solid
color :White to off-white
InChIKey :QZHBYNSSDLTCRG-WUUYCOTASA-N
CAS DataBase Reference :70359-46-5(CAS DataBase Reference)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: 1 mg/ml; PBS (pH 7.2): 3 mg/ml
form :Solid
color :White to off-white
InChIKey :QZHBYNSSDLTCRG-WUUYCOTASA-N
CAS DataBase Reference :70359-46-5(CAS DataBase Reference)
Safety Information
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Description
Brimonidine is a selective α2-adrenergic receptor agonist that lowers intraocular pressure by decreasing aqueous humor synthesis and increasing drainage through uveoscleral outflow. By stimulating α2-adrenergic receptors coupled to their G proteins (Ki = 183 nM), brimonidine inhibits adenylate cyclase activity and reduces cAMP. Furthermore, at 1 mg/kg/day brimonidine has been shown to protect rat retinal ganglion cells against glutamate excitotoxicity by inhibiting glutamate release and blocking the upregulation of NDMA receptor 1 and 2A protein expression.More related product prices
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