ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >Adrenergic Receptor agonists >Brimonidine Tartrate
Brimonidine Tartrate
- CAS No.
- 70359-46-5
- Chemical Name:
- Brimonidine Tartrate
- Synonyms
- Alphagan;UK-14304-18;304 tartrate;AGN-190342-LF;UK 14,304 TARTRATE;AGN190342 tartrate;BRIMONIDINE TARTATE;BRIMONIDINE TARTRATE;Brimonidinne tartrate;Brimonidine tartarate
- CBNumber:
- CB8351621
- Molecular Formula:
- C15H16BrN5O6
- Molecular Weight:
- 442.22
- MOL File:
- 70359-46-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:27
| Melting point | 207-208°C (dec.) |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: 1 mg/ml; PBS (pH 7.2): 3 mg/ml |
| form | Solid |
| color | White to off-white |
| InChIKey | QZHBYNSSDLTCRG-WUUYCOTASA-N |
| CAS DataBase Reference | 70359-46-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P310-P302+P352-P305+P351+P338 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| HS Code | 29332900 | |||||||||
| NFPA 704 |
|
Brimonidine Tartrate price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR2795 | Brimonidine Tartrate pharmaceutical secondary standard, certified reference material | 70359-46-5 | 500MG | ₹20643.28 | 2022-06-14 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| PHR2795 | 500MG | ₹20643.28 | Buy |
Brimonidine Tartrate Chemical Properties,Uses,Production
Description
Brimonidine is an agonist of α2-adrenergic receptors (α2-ARs; Kis = 2.7, 52, and 44 nM for α2A, α2B, and α2C-ARs, respectively, in CHO cells). It is selective for α2-ARs over α1-ARs (Ki = 1,800 nM in human brain). Brimonidine lowers intraocular pressure in DBA/2J mice, a model of glaucoma, to control levels when applied topically to the eye as a 0.1% solution. It also inhibits glutamate release, prevents upregulation of NMDA receptors containing NR1 and NR2A subunits, and protects rat retinal ganglion cells against glutamate excitotoxicity in a rat model of retinal ischemia when administered at a dose of 1 mg/kg per day. Formulations containing brimonidine have been used in the treatment of open-angle glaucoma and ocular hypertension.
Chemical Properties
Off-White Crystalline Solid
Uses
It is an a 2 receptor agonist. It is a drug used to treat glaucoma. It acts via decreasing aqueous humor synthesis
Brimonidine Tartrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 392)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
| Vadivarhe Speciality Chemicals Limited | +91-9028832204 +91-9028832204 | Maharashtra, India | 38 | 58 | Inquiry |
| Alkaloids Private Limited | +91-9866110664 +91-9866110664 | Telangana, India | 25 | 58 | Inquiry |
| PANCHSHEEL ORGANICS LTD | +91-9821053955 +91-9324201019 | Mumbai, India | 82 | 58 | Inquiry |
| Nivika Chemo Pharma Pvt Ltd | +91-9824176501 +91-9824176501 | Gujarat, India | 15 | 58 | Inquiry |
| Viyash Life Sciences Pvt Ltd | +91-4023635052 +91-4023635052 | Telangana, India | 213 | 58 | Inquiry |
| FDC Limited | +912226782653 | Mumbai, India | 30 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Centaur Pharmaceuticals Pvt Ltd | +912266499100 | Mumbai, India | 33 | 58 | Inquiry |
| Unichem Laboratories Ltd | +91-2266888333 +91-2266888333 | Maharashtra, India | 62 | 58 | Inquiry |
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C13H12BrN3C4H6O6
C15H16BrN5O6
C11H10BrN5C4H6O6
C4H6O6C11H10BrN5
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