Brimonidine
- CAS No.
- 59803-98-4
- Chemical Name:
- Brimonidine
- Synonyms
- UK 14,304;UBC;UK 14;RPS27A;CS-1362;UK 14,34;UK-11957;lk14304-18;AGN-190342;BRIMONIDINE
- CBNumber:
- CB9111370
- Molecular Formula:
- C11H10BrN5
- Molecular Weight:
- 292.13
- MOL File:
- 59803-98-4.mol
- Modify Date:
- 2023/9/20 16:58:51
| Melting point | 207.5 °C |
|---|---|
| Boiling point | 432.6±55.0 °C(Predicted) |
| Density | 1.82±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: <0.8 mg/mL |
| form | powder to crystal |
| pka | 7.69±0.10(Predicted) |
| color | Light yellow to Amber to Dark green |
| Merck | 14,1375 |
| CAS DataBase Reference | 59803-98-4(CAS DataBase Reference) |
Brimonidine price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | U104 | UK 14,304 | 59803-98-4 | 5MG | ₹7999.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | U104 | UK 14,304 | 59803-98-4 | 25MG | ₹28913.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | U104 | UK 14,304 | 59803-98-4 | 100MG | ₹94199.15 | 2022-06-14 | Buy |
| TCI Chemicals (India) | B4132 | Brimonidine | 59803-98-4 | 200MG | ₹8400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B4132 | Brimonidine | 59803-98-4 | 1G | ₹14200 | 2022-05-26 | Buy |
Brimonidine Chemical Properties,Uses,Production
Description
Launched in the US for open-angle glaucoma and ocular hypertension, brimonidine is a relatively selective and potent α2a,-adrenergic agonist with low affinity for the imidazoline l1 receptor. Topical application reduces intraocular pressure. This bypasses any central hypotensive effects at the l1 receptor (which can also give rise to a decrease in blood pressure and heart rate) if given systemically, since topical application results in low plasma levels concomitant with rapid systemic elimination. Brimonidine can be prepared in a four-step sequence from 4-nitrophenylenediamine.
Chemical Properties
Yellow Solid
Uses
a2-Adrenoceptor agonist. Antiglaucoma
Hazard
A poison by ingestion.
Biological Activity
Full α 2 adrenergic agonist. Centrally active following systemic administration in vivo . Also available as part of the α 2 -Adrenoceptor Tocriset™ and Mixed Adrenergic Tocriset™ .
Brimonidine Preparation Products And Raw materials
Global( 255)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
| Vijaya Pharma And Life Science | +91-8939866271 +91-8939866271 | Tamil Nadu, India | 320 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Nivi Exim | 91-22-27576333 | Maharashtra, India | 61 | 58 | Inquiry |
| Avience chemicals and pharmaceuticals | 91-7046079465 | Gujarat, India | 180 | 58 | Inquiry |
| Athos Chemicals | 91-9998858909 | Gujarat, India | 315 | 58 | Inquiry |
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59803-98-4
C11H10BrN5
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