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Cinchonidine

CAS No.: 485-71-2

Chemical Name:: Cinchonidine

Synonyms: (-)-CINCHONIDINE;(-)-Cinchonidine;Cinchondine;(8s,9r)-cinchonidine;(8a,9R)-Cinchonan-9-ol;L-Cin;A-QUINIDINE;Cinchovatine;CINCHONIDINE;2'-Hydroxy-4'

CBNumber:: CB5246395

Molecular Formula:: C19H22N2O

Molecular Weight:: 294.39

MOL File:: 485-71-2.mol

Modify Date:: 2023/8/30 13:35:17

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Cinchonidine Properties

Melting point	204-206 °C(lit.)
alpha	-115 º (c=1, EtOH)
Boiling point	436.16°C (rough estimate)
Density	1.0863 (rough estimate)
vapor pressure	0Pa at 25℃
refractive index	-107.5 ° (C=1, EtOH)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	0.25g/l
form	Crystalline Powder
pka	5.80, 10.03(at 25℃)
color	White to cream
PH	9 (0.2g/l, H2O, 20℃)
optical activity	[α]23/D 109.2°, c = 1.5 in ethanol
Water Solubility	Insoluble
Sensitive	Light Sensitive
Merck	14,2286
BRN	89690
Stability	Stable, but light-sensitive. Incompatible with strong oxidizing agents.
InChIKey	KMPWYEUPVWOPIM-NAHPKXJFSA-N
LogP	2.68 at 25℃
CAS DataBase Reference	485-71-2(CAS DataBase Reference)
NIST Chemistry Reference	Cinchonidine(485-71-2)
EPA Substance Registry System	Cinchonan-9-ol, (8.alpha.,9R)- (485-71-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H317-H319

Precautionary statements

P261-P264-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-42/43-36/37/38-20/22-48/22-43-22-63

Safety Statements

22-24/25-36/37-36-26

RIDADR

1544

WGK Germany

RTECS

GD2975000

TSCA

Yes

HazardClass

6.1(b)

PackingGroup

III

HS Code

29392900

Toxicity

LD50 i.p. in rats: 206 mg/kg (Johnson, Poe); LD50 orally in quail: >316 mg/kg (Schafer)

NFPA 704

	1
2		1

Cinchonidine price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	C80407	Cinchonidine 96%	485-71-2	10G	₹6320	2022-06-14	Buy
Sigma-Aldrich(India)	C80407	Cinchonidine 96%	485-71-2	100G	₹19670	2022-06-14	Buy
Sigma-Aldrich(India)	44703	(−)-Cinchonidine analytical standard	485-71-2	100MG	₹5477.45	2022-06-14	Buy
ALFA India	ALF-A18796-22	(-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine	485-71-2	100g	₹21464	2022-05-26	Buy
TCI Chemicals (India)	C0347	Cinchonidine	485-71-2	25G	₹6500	2022-05-26	Buy

Product number	Packaging	Price	Buy
C80407	10G	₹6320	Buy
C80407	100G	₹19670	Buy
44703	100MG	₹5477.45	Buy
ALF-A18796-22	100g	₹21464	Buy
C0347	25G	₹6500	Buy

Cinchonidine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

Cinchonidine occurs in most varieties of Cinchona bark and is stereoisomeric with Cinchonine. Cinchonidine exhibits Antimalarial properties.

Definition

ChEBI: 8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis.

Purification Methods

Crystallise cinchonidine from aqueous EtOH. For the N-benzylcinchonidinium chloride see above entry in this section. [Beilstein 23 III/IV 2824.]

Cinchonidine Preparation Products And Raw materials

Raw materials

Preparation Products

Esfenvalerate 1,1'-Bis (di-t-butylphosphino)ferrocene palladium dichloride, (S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE Fosinopril 1,1'-SPIROBIINDANE-7,7'-DIOL

1,1'-Bis(di-tert-butylphosphino)ferrocene N-Benzylcinchonidinium chloride (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE Benazepril (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-PHENOXY

QUININE SULFATE 2-(Dicyclohexylphosphino)biphenyl (11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE (R)-7,7'-BIS(DIPHENYLPHOSPHINO)-1,1'-SPIROBIINDANE (S)-1,1'-SPIROBIINDANE-7,7'-DIOL

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Cinchonidine Suppliers

Global( 398)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Chempifine Chemicals	+91-2225667766 +91-2225667766	Punjab, India	144	58	Inquiry
Prism Industries Ltd	+91-9825050731 +91-9227406992	Gujarat, India	28	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6913	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Vital Laboratories Pvt., Ltd.	91-22-26183641	Maharashtra, India	16	58	Inquiry
Biopharmacule Speciality Chemicals P Ltd (India)	+91 40 6462 1866	Hyderabad, India	526	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
Innovative Synthetic Molecules	+91 40-24111684	Hyderabad, India	527	58	Inquiry
Opulent Pharma	08068441147Ext 981	Gujarat, India	810	58	Inquiry

Supplier	Advantage
Chempifine Chemicals	58
Prism Industries Ltd	58
Alfa Aesar	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
SynZeal Research Pvt Ltd	58
Vital Laboratories Pvt., Ltd.	58
Biopharmacule Speciality Chemicals P Ltd (India)	58
Pharma Affiliates	58
Innovative Synthetic Molecules	58
Opulent Pharma	58

Cinchonidine Spectrum

Cinchonidine(485-71-2)MS Cinchonidine(485-71-2)¹HNMR Cinchonidine(485-71-2)¹³CNMR Cinchonidine(485-71-2)IR1 Cinchonidine(485-71-2)IR2 Cinchonidine(485-71-2)Raman

485-71-2(Cinchonidine)Related Search:

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Cinchonine Triethoxyvinylsilane Methanol DL-CARNITINE N-Vinyl-2-pyrrolidone

Vinylmagnesium bromide p-Anisaldehyde (Trifluoromethoxy)benzene

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(8-alpha,9r)-cinchonan-9-o (8alpha,9theta)-cinchonan-9-o 2-Quinuclidinemethanol, alpha-4-quinolyl-5-vinyl- Cinchonan-9-ol Cinchonan-9-ol, (8alpha,9R)- Cinchovatine Cinchonidinederivedcatalyst {5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl}(quinolin-4-yl)Methanol Cinchonidine, 98.5-101% 100GR Cinchonidine, 98.5-101% 25GR CINCHONIDINE 1-Cinchonidine (-)-Cinchonidine (total base), may cont. up to 5% quinine cinchonidine .base Cinchonidine ,98.5% Cinchonidine,()-Cinchonidine (-)-CINCHONIDINE FOR RESOLUTION OF RACEM (-)-Cinchonidine, 99%, may contain up to 5% quinine (-)-Cinchonidine for resolution of racemates for synthesis CINCHONAN-9-OL,(8,9R)- A-QUINIDINE ALPHA-QUINIDINE (8alpha,9r)-cinchonan-9-ol CINCHONIDINE: CINCHONAN-9-OL,(8,9R)-, Cinchonidine,99% [8α,9R]-Cinchonan-9-ol Cinchonidine, 98.5-101% CINCHONIDINE(RG) L-CINCHONIDINE Cinchonidine (base and/or unspecified salts) 4-Quinolyl-(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol (R)-Quinolin-4-yl[(2S,4S,5R)-5-vinyl-1-azabicyclo[2.2.2]oct-2-yl]methanol (8S,9R)-Cinchonan-9-ol (-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine (R)-[(4S,5R,7S)-5-Ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-quinolin-4-ylmethanol (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol (3alpha,4beta,8alpha,9S)-cinchonan-9-ol (3alpha,9R)-9-hydroxycinchonan-1-ium (4beta,8alpha,9R)-cinchonan-1-ium-9-ol (8alpha,9R)-9-hydroxycinchonan-1-ium (9R)-cinchonan-1-ium-9-ol (9R)-cinchonan-9-ol Quinine Sulphate EP Impurity B L-Cin Cinchonidine, 98%, for synthesis Cinchonidine > Quinine EP Impurity B (R)-Quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol Cinchonidine USP/EP/BP [(2R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol 2'-Hydroxy-4' (8s,9r)-cinchonidine Cinchondine (-)-CINCHONIDINE (-)-Cinchonidine (8a,9R)-Cinchonan-9-ol Cinchonidine (8CI) (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](quinolin-4-yl)methanol (cinchonidine)