Cefapirin sodium
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- ₹26975.9
- Product name: Cefapirin sodium
- CAS: 24356-60-3
- MF: C17H18N3NaO6S2
- MW: 447.46
- EINECS:246-194-2
- MDL Number:MFCD07793329
- Synonyms:cephapirin sodium crystalline;sodium (6R-trans)-3-(acetoxymethyl)-8-oxo-7-[(4-pyridylthio)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ;CEPHAPIRIN BEUZATHINE;5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 3-(acetyloxy)methyl-8-oxo-7-(4-pyridinylthio)acetylamino-, monosodium salt, (6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-[2-(4-pyridylthio)acetamido]-, acetate (ester), monosodium salt (8CI);5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-8-oxo-7-[[(4-pyridinylthio)acetyl]amino]-, monosodium salt, (6R-trans)-;7-[α-(4-Pyridylthio)acetamido]cephalosporanic acid sodium salt;Ambrocef
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSMB00605
- Product descriptionCephapirin sodium
- Packaging25MG
- Price₹26975.9
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SMB00605 | Cephapirin sodium | 25MG | ₹26975.9 | 2022-06-14 | Buy |
Properties
Melting point :>177°C (dec.)
alpha :+152～+170゜(25℃/D)(c=2,H2O)(calculated on the dehydrous basis)
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in water, practically insoluble in methylene chloride.
form :powder
pka :pKa 2.15 (Uncertain)
color :Light Beige to Beige
InChIKey :VGEOUKPOQQEQSX-OALZAMAHSA-M
CAS DataBase Reference :24356-60-3(CAS DataBase Reference)
alpha :+152～+170゜(25℃/D)(c=2,H2O)(calculated on the dehydrous basis)
storage temp. :Inert atmosphere,2-8°C
solubility :Soluble in water, practically insoluble in methylene chloride.
form :powder
pka :pKa 2.15 (Uncertain)
color :Light Beige to Beige
InChIKey :VGEOUKPOQQEQSX-OALZAMAHSA-M
CAS DataBase Reference :24356-60-3(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
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Description
Cephapirin sodium (Cefapirin sodium), a semisynthetic cephalosporin antibiotic, is bactericidal against strains of gram-positive and gram-negative bacteria.Cephapirin is closely resembles cephalothin in chemical and pharmacokinetic properties. Cephapirin, have cephalosporanic acid core with the acetyloxymethyl group at the 3rd position and having IUPAC name (6R,7R)-3-(Acetoxymethy)-8- oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia- 1-azabicyclo [4.2.0] oct-2-ene-2-carboxylic acid. It is unstable in acid and must be administered parenteral. It has similar mechanism as other cephalosporins. It is marketed under the trade name Cefadyl. It is effective against a wide variety of gram-positive and gramnegative bacteria; used as the sodium salt. Among the most serious adverse reactions of cefapirin, that is， neutropenia, leukopenia, anemia, bone marrowdepression, and allergic reactions, it has been discontinued in the United States (Wiesner, 1972).
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