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ChemicalBook > Product Catalogue >API >Antibiotics >Cephalosporins Drugs >Cefotetan

Cefotetan

Cefotetan Structure
  • ₹3000 - ₹9800
  • Product name: Cefotetan
  • CAS: 69712-56-7
  • MF: C17H17N7O8S4
  • MW: 575.62
  • EINECS:274-093-3
  • MDL Number:MFCD00864983
  • Synonyms:CEFOTETAN;CEFOTETAN DISODIUM SALT;disodium (7r)-7-[[4-(carbamoyl-carboxylato-methylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, (6R,7S)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, disodium salt, [6R-(6α,7α)]-;Apatef;Ceftenon;Cepan Darvilen
2 prices
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Brand

  • TCI Chemicals (India)

Package

  • 25MG
  • 250MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC2936
  • Product descriptionCefotetan
  • Packaging25MG
  • Price₹3000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2936
  • Product descriptionCefotetan
  • Packaging250MG
  • Price₹9800
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2936 Cefotetan 25MG ₹3000 2022-05-26 Buy
TCI Chemicals (India) C2936 Cefotetan 250MG ₹9800 2022-05-26 Buy

Properties

Melting point :173-178°C (dec.)
Density :1.5157 (rough estimate)
refractive index :1.7400 (estimate)
storage temp. :Store at 0-5°C
solubility :DMSO (Slightly), Methanol (Very Slightly)
form :Solid
pka :1.69±0.41(Predicted)
color :White to Off-White
Merck :14,1934
Stability :Hygroscopic
InChIKey :SRZNHPXWXCNNDU-IXOPCIAXSA-N
CAS DataBase Reference :69712-56-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cefotetan is comparatively stable, lasting for approximately 24 hours at room temperature when reconstituted. Slight yellowing and slight darkening produce materials that are still acceptable for therapy. Cefotetan is chemically incompatible with tetracycline, aminoglycosides, and with heparin, often forming precipitates with them. With respect to its molecular mode of action, it has a special affinity for PBP-3 of Gram-negative bacteria, consequently producing filamentous forms. It also binds well with PBP-1A and -1B,therefore leading to cell lysis and death. Whereas it is stable to a wide range of β-lactamases, it also is a potent inducer in some bacteria.

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