Cilastatin sodium
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- ₹5200 - ₹31186.83
- Product name: Cilastatin sodium
- CAS: 81129-83-1
- MF: C16H25N2O5S.Na
- MW: 380.44
- EINECS:279-694-4
- MDL Number:MFCD08459332
- Synonyms:Cilastatine;Cilastatin sodium;Sodium 7-(2-amino-2-carboxy-ethyl)sulfanyl-2-(2,2-dimethylcyclopropyl)carbonylamino-hept-2-enoate;Sodium hydrogen 7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate;Sodium Cilastatin;[R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic acid monosodium salt;(Z)-7-[(R)-2-Amino-2-carboxyethylthio]-2-[(S)-2,2-dimethylcyclopropylcarbonylamino]-2-heptenoic acid 1-sodium salt;(2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoicacidsodiumsalt
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
Package
- 50MG
- 100MG
- 2ML
- ManufacturerSigma-Aldrich(India)
- Product numberSML1283
- Product descriptionCilastatin sodium Ready Made Solution 50?mg/mL in DMSO/H2O, 1:1
- Packaging2ML
- Price₹17236.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC5743
- Product descriptionCilastatin sodium salt ≥98% (HPLC)
- Packaging100MG
- Price₹31186.83
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberC3547
- Product descriptionCilastatin Sodium Salt
- Packaging50MG
- Price₹5200
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML1283 | Cilastatin sodium Ready Made Solution 50?mg/mL in DMSO/H2O, 1:1 | 2ML | ₹17236.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C5743 | Cilastatin sodium salt ≥98% (HPLC) | 100MG | ₹31186.83 | 2022-06-14 | Buy |
TCI Chemicals (India) | C3547 | Cilastatin Sodium Salt | 50MG | ₹5200 | 2022-05-26 | Buy |
Properties
Melting point :>160°C (dec.)
Flash point :87℃
storage temp. :2-8°C
solubility :Very soluble in water and in methanol, slightly soluble in anhydrous ethanol, very slightly soluble in dimethyl sulfoxide, practically insoluble in acetone and in methylene chloride.
form :Solid
pka :pKa1 2.0; pKa2 4.4; pKa3 9.2(at 25℃)
color :White
biological source :synthetic (organic)
Water Solubility :water: 10mg/mL, clear, colorless to faintly yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
CAS DataBase Reference :81129-83-1(CAS DataBase Reference)
Flash point :87℃
storage temp. :2-8°C
solubility :Very soluble in water and in methanol, slightly soluble in anhydrous ethanol, very slightly soluble in dimethyl sulfoxide, practically insoluble in acetone and in methylene chloride.
form :Solid
pka :pKa1 2.0; pKa2 4.4; pKa3 9.2(at 25℃)
color :White
biological source :synthetic (organic)
Water Solubility :water: 10mg/mL, clear, colorless to faintly yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
CAS DataBase Reference :81129-83-1(CAS DataBase Reference)
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
Cilastatin Na (81129-83-1) is a dehydropeptidase-1 inhibitor. Inhibits the proteolytic conversion of leukotriene D4?to E4.1? Inhibits the mammalian β-lactamase renal dipeptidase (dehydropeptidase-1, DPEP1) and thus is used as an antibacterial adjunct to extend the half-life of β-lactam antibiotics.2?Cilastatin also inhibits bacterial metallo-β-lactamase and thereby may block resistance to the carbapenem family of antibiotics in certain bacteria.3? Suppresses invasion and metastasis of DPEP1-expressing tumor cells.4More related product prices
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