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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Other antineoplastic Drugs >Cisplatin

Cisplatin

Cisplatin Structure
  • ₹3501 - ₹593827.8
  • Product name: Cisplatin
  • CAS: 15663-27-1
  • MF: Cl2H6N2Pt
  • MW: 300.04
  • EINECS:239-733-8
  • MDL Number:MFCD00011623
  • Synonyms:peyrone’schloride ;platidiam ;platidiamlachemabrno ;tr170 ;cis-Platinous diamine dichloroplatin;cis-Diaminedichloroplatinum(II);CISPLATIN (CIS-DICHLORODIAMMINEPLATINUM(II));CIS-DIAMINE PLATINUM-(II)-DICHLORIDE
Price21 Properties Safety Information Description
21 prices
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Brand

  • Sigma-Aldrich(India)
  • ALFA India
  • Sigma-Aldrich
  • TCI Chemicals (India)
  • ottokemi

Package

  • 25MG
  • 50MG
  • 100MG
  • 200MG
  • 250MG
  • 0.25G
  • 500mg
  • 1G
  • 1gm
  • 5G
  • 50G
  • ManufacturerSigma-Aldrich(India)
  • Product number479306
  • Product descriptioncis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis
  • Packaging50G
  • Price₹593827.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP4394
  • Product descriptioncis-Diammineplatinum(II) dichloride crystalline
  • Packaging1G
  • Price₹56732.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number479306
  • Product descriptioncis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis
  • Packaging5G
  • Price₹53379.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number479306
  • Product descriptioncis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis
  • Packaging1G
  • Price₹35464.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP4394
  • Product descriptioncis-Diammineplatinum(II) dichloride crystalline
  • Packaging250MG
  • Price₹21167.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1624
  • Product descriptionCisplatin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging200MG
  • Price₹16960.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number232120
  • Product descriptionCisplatin - CAS 15663-27-1 - Calbiochem Cisplatin - CAS 15663-27-1, is a platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via c
  • Packaging50MG
  • Price₹15909.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP4394
  • Product descriptioncis-Diammineplatinum(II) dichloride crystalline
  • Packaging100MG
  • Price₹10622.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP4394
  • Product descriptioncis-Diammineplatinum(II) dichloride crystalline
  • Packaging25MG
  • Price₹3984.9
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-010471-MD
  • Product descriptioncis-Diamminedichloroplatinum(II), Pt 64.5% min.
  • Packaging250mg
  • Price₹13609
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-010471-01
  • Product descriptioncis-Diamminedichloroplatinum(II), Pt 64.5% min.
  • Packaging0.25G
  • Price₹13045
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number479306
  • Product descriptioncis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis
  • Packaging50G
  • Price₹593827.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number479306
  • Product descriptioncis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis
  • Packaging5G
  • Price₹53379.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number479306
  • Product descriptioncis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis
  • Packaging1G
  • Price₹35464.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number232120
  • Product descriptionCisplatin - CAS 15663-27-1 - Calbiochem Cisplatin - CAS 15663-27-1, is a platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation.
  • Packaging50MG
  • Price₹15909.99
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD3371
  • Product descriptioncis-Diammineplatinum(II) Dichloride
  • Packaging100MG
  • Price₹4100
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 479306 cis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis 50G ₹593827.8 2022-06-14 Buy
Sigma-Aldrich(India) P4394 cis-Diammineplatinum(II) dichloride crystalline 1G ₹56732.1 2022-06-14 Buy
Sigma-Aldrich(India) 479306 cis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis 5G ₹53379.9 2022-06-14 Buy
Sigma-Aldrich(India) 479306 cis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis 1G ₹35464.5 2022-06-14 Buy
Sigma-Aldrich(India) P4394 cis-Diammineplatinum(II) dichloride crystalline 250MG ₹21167.7 2022-06-14 Buy
Sigma-Aldrich(India) PHR1624 Cisplatin Pharmaceutical Secondary Standard; Certified Reference Material 200MG ₹16960.8 2022-06-14 Buy
Sigma-Aldrich(India) 232120 Cisplatin - CAS 15663-27-1 - Calbiochem Cisplatin - CAS 15663-27-1, is a platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via c 50MG ₹15909.99 2022-06-14 Buy
Sigma-Aldrich(India) P4394 cis-Diammineplatinum(II) dichloride crystalline 100MG ₹10622.7 2022-06-14 Buy
Sigma-Aldrich(India) P4394 cis-Diammineplatinum(II) dichloride crystalline 25MG ₹3984.9 2022-06-14 Buy
ALFA India ALF-010471-MD cis-Diamminedichloroplatinum(II), Pt 64.5% min. 250mg ₹13609 2022-05-26 Buy
ALFA India ALF-010471-01 cis-Diamminedichloroplatinum(II), Pt 64.5% min. 0.25G ₹13045 2022-05-26 Buy
Sigma-Aldrich 479306 cis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis 50G ₹593827.8 2022-06-14 Buy
Sigma-Aldrich 479306 cis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis 5G ₹53379.9 2022-06-14 Buy
Sigma-Aldrich 479306 cis-Diamineplatinum(II) dichloride ≥99.9% trace metals basis 1G ₹35464.5 2022-06-14 Buy
Sigma-Aldrich 232120 Cisplatin - CAS 15663-27-1 - Calbiochem Cisplatin - CAS 15663-27-1, is a platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation. 50MG ₹15909.99 2022-06-14 Buy
TCI Chemicals (India) D3371 cis-Diammineplatinum(II) Dichloride 100MG ₹4100 2022-05-26 Buy
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Properties

Melting point :270 °C (lit.)
Density :3,7 g/cm3
storage temp. :2-8°C
solubility :Soluble in DMF. Insoluble in most common solvents
form :crystalline
color :yellow
Water Solubility :<0.1 g/100 mL at 19 ºC
Merck :14,2317
Exposure limits :ACGIH: TWA 0.002 mg/m3
NIOSH: IDLH 4 mg/m3; TWA 0.002 mg/m3 Stability :Stable. Incompatible with oxidizing agents, aluminium, antioxidants.
CAS DataBase Reference :15663-27-1(CAS DataBase Reference)
IARC :2A (Vol. 26, Sup 7) 1987, 1 (Vol. 76, 100A) 2012
EPA Substance Registry System :Cisplatin (15663-27-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cisplatin is a platinum-containing compound that acts as an alkylating agent, interacting with DNA to form adducts which interfere with replication and transcription, culminating in apoptosis. It is used, alone or in combination therapy, in the treatment of several types of cancer, including testicular, ovarian, cervical, bladder, and lung cancers. Cisplatin also inhibits the RecA recombinase of M. tuberculosis (IC50 = 2 μM), blocking protein splicing and cell growth.

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Jigs Chemical ltd AVD pharmaceuticals Pvt Ltd Bulat Pharmaceutical Pvt Ltd Arora Matthey Limited Cipla Ltd Sun Pharmaceutical Industries Ltd Green Vision Life Sciences Pvt Ltd. Raising Sun Pharma Laurus Labs Ltd Ralington Pharma