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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >CYTOCHALASIN A

CYTOCHALASIN A

CYTOCHALASIN A Structure
  • ₹13005 - ₹110079
  • Product name: CYTOCHALASIN A
  • CAS: 14110-64-6
  • MF: C29H35NO5
  • MW: 477.59
  • EINECS:237-964-9
  • MDL Number:MFCD00005935
  • Synonyms:(7S,13E,16R,21E)-7-Hydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,20,23-trione;5,5-Didehydrophomin;Dehydrophomin;Cytochalasin dreschslera dematioidea;Cytochalasin A 5-Dehydrophomin Dehydrophomin;7(S)-hydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,20,23-trione ;2H-Oxacyclotetradecino2,3-disoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (3E,9R,11E,12aS,13S,15S,15aS,16S,18aS)-;CYTOCHALASIN A FROM DRESCHSLERA DEMATIOIDEA
3 prices
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Brand

  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 1MG
  • 10mg
  • ManufacturerSigma-Aldrich(India)
  • Product numberC6637
  • Product descriptionCytochalasin A from Drechslera dematioidea
  • Packaging1MG
  • Price₹14267.35
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number C 3040
  • Product descriptionCytochalasin A, from drechslera dematioidea 99%
  • Packaging10mg
  • Price₹110079
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number C 3040
  • Product descriptionCytochalasin A, from drechslera dematioidea 99%
  • Packaging1mg
  • Price₹13005
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C6637 Cytochalasin A from Drechslera dematioidea 1MG ₹14267.35 2022-06-14 Buy
ottokemi C 3040 Cytochalasin A, from drechslera dematioidea 99% 10mg ₹110079 2022-05-26 Buy
ottokemi C 3040 Cytochalasin A, from drechslera dematioidea 99% 1mg ₹13005 2022-05-26 Buy

Properties

Melting point :190-191 °C
Boiling point :725.1±60.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :ethanol: 20 mg/mL, clear, colorless
pka :13.54±0.70(Predicted)
form :Powder
color :White
Water Solubility :Soluble in DMF, DMSO, ethanol and acetone. Insoluble in water.
Sensitive :Light Sensitive
BRN :949521
LogP :1.849 (est)
EPA Substance Registry System :Cytochalasin A (14110-64-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin A is an oxidized analog of cytochalasin B which uniquely inhibits HIV-1 protease (IC50 = 3 μM). Cytochalasins A and B differ from other cytochalasins in being able to rapidly and reversibly inhibit glucose transport by competitively binding glucose transporters (Ki = 4.0 and 0.6 μM, respectively). Cytochalasin A also induces the phosphorylation of the tyrosine phosphatase PTP3 of Dictyostelium, activating STATc.

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