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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiseptics & Disinfectants Drugs >Dequalinium chloride

Dequalinium chloride

Dequalinium chloride Structure
  • ₹11745.13
  • Product name: Dequalinium chloride
  • CAS: 522-51-0
  • MF: C30H40Cl2N4
  • MW: 527.57
  • EINECS:208-330-9
  • MDL Number:MFCD00063502
  • Synonyms:1,1'-DECAMETHYLENEBIS(4-AMINOQUINALDINIUM CHLORIDE);1,1'-DECAMETHYLENEBIS(4-AMINOQUINALDINIUM) DICHLORIDE;1,1'-(1,10-DECANEDIYL)BIS(4-AMINO-2-METHYLQUINOLINIUM) DICHLORIDE;DEQUALINIUM CHLORIDE;dequadinchloride ;dequavagyn ;dequavet ;efisol
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1300
  • Product descriptionDequalinium chloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹11745.13
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1300 Dequalinium chloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹11745.13 2022-06-14 Buy

Properties

Melting point :≥300 °C(lit.)
storage temp. :2-8°C
solubility :Slightly soluble in water and in ethanol (96 per cent).
form :Solid
color :Beige
Merck :13,2930
Stability :Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey :LTNZEXKYNRNOGT-UHFFFAOYSA-N
CAS DataBase Reference :522-51-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dequalinium chloride is a selective blocker of apamin-sensitive K+ channels and inhibitor of XIAP (X-linked inhibitor of apoptosis protein). The compound has induced apoptosis in leukemia B4 cells through disturbance of mitochondrial function, oxidative stress, and downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways.

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