DIHYDROMETHYSTICIN
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- ₹42618.03
- Product name: DIHYDROMETHYSTICIN
- CAS: 19902-91-1
- MF: C15H16O5
- MW: 276.28
- EINECS:
- MDL Number:MFCD00221731
- Synonyms:6-(2-(1,3-benzodioxol-5-yl)ethyl)-5,6-dihydro-4-methoxy-2h-pyran-2-on(s) ;6-dihydro-4-methoxy-6-(3,4-(methylenedioxy)phenethyl)-(s)-2h-pyran-2-on ;7,8-dihydromethysticin ;dhm ;DIHYDROMETHYLSTICIN;7,8-DIHYDROMETHYLSTICIN;5,6-Dihydro-4-methoxy-6-[2-(1,3-benzodioxol-5-yl)ethyl]-2H-pyran-2-one;6-[2-(1,3-Benzodioxol-5-yl)ethyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product number52007
- Product description(+)-Dihydromethysticin analytical standard
- Packaging5MG
- Price₹42618.03
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 52007 | (+)-Dihydromethysticin analytical standard | 5MG | ₹42618.03 | 2022-06-14 | Buy |
Properties
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
Boiling point :476.1±45.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
Melting point :117-118 °C
form :Solid
color :White to Off-White
BRN :91699
Stability :Hygroscopic
InChIKey :RSIWXFIBHXYNFM-NSHDSACASA-N
LogP :1.810 (est)
solubility :Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
Boiling point :476.1±45.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
Melting point :117-118 °C
form :Solid
color :White to Off-White
BRN :91699
Stability :Hygroscopic
InChIKey :RSIWXFIBHXYNFM-NSHDSACASA-N
LogP :1.810 (est)
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
Dihydromethysticin is a kavalactone originally isolated from P. methysticum (kava-kava) that has diverse biological activities, including efflux transporter inhibitory, antinociceptive, and neuroprotective properties. Dihydromethysticin is a P-glycoprotein (P-gp) inhibitor that increases uptake of the P-gp substrate calcein AM by 50% in P388 mouse leukemia cancer cells overexpressing P-gp when used at a concentration of 54.6 μM. Dihydromethysticin (275 mg/kg) has analgesic activity, increasing the latency to tail withdrawal in the tail-flick assay in mice. It also decreases the infarct size in a mouse model of ischemia induced by microbipolar coagulation of the left middle cerebral artery (MCA) when administered at a dose of 10 mg/kg.Related product price
- DIHYDROMETHYSTICIN
₹42618.03 - 5,6-DIHYDRO-2H-PYRAN-2-ONE
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