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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >DL-Sulforaphane

DL-Sulforaphane

DL-Sulforaphane Structure
  • ₹13964.25 - ₹29500
  • Product name: DL-Sulforaphane
  • CAS: 4478-93-7
  • MF: C6H11NOS2
  • MW: 177.29
  • EINECS:200-001-8
  • MDL Number:MFCD00198068
  • Synonyms:sulforafan ;R-SULFORAPHANE;R,S-SULFORAPHANE;SULFORAPHANE, L-;SULFORAPHANE, DL-;SULFORAPHANE, D-;S-SULFORAPHANE;Methyl(4-isothiocyanatobutyl) sulfoxide
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberS4441
  • Product descriptionDL-Sulforaphane ≥90% (HPLC), synthetic, liquid
  • Packaging5MG
  • Price₹13964.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number574215
  • Product descriptionD,L-Sulforaphane - CAS 4478-93-7 - Calbiochem An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in c
  • Packaging25MG
  • Price₹29500
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) S4441 DL-Sulforaphane ≥90% (HPLC), synthetic, liquid 5MG ₹13964.25 2022-06-14 Buy
Sigma-Aldrich(India) 574215 D,L-Sulforaphane - CAS 4478-93-7 - Calbiochem An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in c 25MG ₹29500 2022-06-14 Buy

Properties

Boiling point :125-135°C
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: 40 mg/mL, soluble
form :liquid
color :slightly yellow
Stability :Light Sensitive
LogP :0.407 (est)
CAS DataBase Reference :4478-93-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. Unless activated by inflammatory, environmental, or oxidative stressors, Nrf2 is sequestered in the cytoplasm by its repressor, Keap1. Because of its protective capabilities, small molecules that activate Nrf2 signaling are being examined as potential anti-cancer or anti-inflammatory agents. Sulforaphane is an isothiocyanate derived from cruciferous vegetables, including broccoli, that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression. At 15 μM, sulforaphane inhibits class I and II HDAC activity and suppresses tumor growth by inducing cell cycle arrest and apoptosis selectively in various cancerous prostate epithelial cells without affecting normal cells.

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