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ChemicalBook > Product Catalogue >Biochemical Engineering >Natural Products >Celastrol

Celastrol

Celastrol Structure
  • ₹20556.68 - ₹81772.05
  • Product name: Celastrol
  • CAS: 34157-83-0
  • MF: C29H38O4
  • MW: 450.61
  • EINECS:636-472-5
  • MDL Number:MFCD03424073
  • Synonyms:(9β,13α,14β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oicacid;Celastrol ,98%;(2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid;10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylic acid;3-Hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid;Celastrol(Tripterine);NSC70931;(2r,4as,6as,6ar,14as,14br)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC2737
  • Product descriptionCelastrol
  • Packaging25MG
  • Price₹24400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC0869
  • Product descriptionCelastrol ≥98% (HPLC), solid
  • Packaging10MG
  • Price₹20556.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC0869
  • Product descriptionCelastrol ≥98% (HPLC), solid
  • Packaging50MG
  • Price₹81772.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2737 Celastrol 25MG ₹24400 2022-05-26 Buy
Sigma-Aldrich(India) C0869 Celastrol ≥98% (HPLC), solid 10MG ₹20556.68 2022-06-14 Buy
Sigma-Aldrich(India) C0869 Celastrol ≥98% (HPLC), solid 50MG ₹81772.05 2022-06-14 Buy

Properties

Melting point :219-230°C
Boiling point :645.7±55.0 °C(Predicted)
Density :1.2
storage temp. :-20°C
solubility :DMSO: >10mg/mL
pka :4.78±0.70(Predicted)
form :solid
color :red
λmax :424nm(MeOH)(lit.)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChIKey :KQJSQWZMSAGSHN-JJWQIEBTSA-N
LogP :7.080 (est)
CAS DataBase Reference :34157-83-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

A variety of natural products from plant sources, particularly flavonoids, have long been observed to have antioxidant activity with potential benefits for human health. Antioxidant triterpenes are less common. Celastrol is a triterpenoid antioxidant compound isolated from Chinese thunder god vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 μM, equivalent to about 15 times the antioxidant potency of α-tocopherol.

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