Triptolide
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- ₹10400 - ₹69821.25
- Product name: Triptolide
- CAS: 38748-32-2
- MF: C20H24O6
- MW: 360.4
- EINECS:683-214-2
- MDL Number:MFCD00210565
- Synonyms:TRIPTOLIDE;TRIPTOLIDE, TRIPTERYGIUM WILFORDII;,7as,7bs,8as,8bs)- ;triptolid ;Triptolide, >=98%;TriptolidefromTripterygium wilfordii≥ 98% (HPLC);Triptolide(TPL);TRIPTOLIDE TLC
6 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
- TCI Chemicals (India)
- SRL
Package
- 1MG
- 5MG
- 10MG
- ManufacturerSigma-Aldrich(India)
- Product number645900
- Product descriptionTriptolide, Tripterygium wilfordii - CAS 38748-32-2 - Calbiochem A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent
- Packaging1MG
- Price₹14100
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT3652
- Product descriptionTriptolide from Tripterygium wilfordii, ≥98% (HPLC), solid
- Packaging1MG
- Price₹17612.28
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number645900
- Product descriptionTriptolide, Tripterygium wilfordii - CAS 38748-32-2 - Calbiochem A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent
- Packaging5MG
- Price₹56740
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT3652
- Product descriptionTriptolide from Tripterygium wilfordii, ≥98% (HPLC), solid
- Packaging5MG
- Price₹69821.25
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberT2899
- Product descriptionTriptolide
- Packaging10MG
- Price₹10400
- Updated2022-05-26
- Buy
- ManufacturerSRL
- Product number35416
- Product descriptionTriptolide ex. Tripterigium Wilfordii for cell culture, 98%
- Packaging5mg
- Price₹15000
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 645900 | Triptolide, Tripterygium wilfordii - CAS 38748-32-2 - Calbiochem A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent | 1MG | ₹14100 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T3652 | Triptolide from Tripterygium wilfordii, ≥98% (HPLC), solid | 1MG | ₹17612.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 645900 | Triptolide, Tripterygium wilfordii - CAS 38748-32-2 - Calbiochem A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent | 5MG | ₹56740 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T3652 | Triptolide from Tripterygium wilfordii, ≥98% (HPLC), solid | 5MG | ₹69821.25 | 2022-06-14 | Buy |
| TCI Chemicals (India) | T2899 | Triptolide | 10MG | ₹10400 | 2022-05-26 | Buy |
| SRL | 35416 | Triptolide ex. Tripterigium Wilfordii for cell culture, 98% | 5mg | ₹15000 | 2022-05-26 | Buy |
Properties
Melting point :226-227°C
alpha :D25 -154°
Boiling point :412.43°C (rough estimate)
Density :1.1656 (rough estimate)
refractive index :1.4450 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :solid
pka :14.25±0.60(Predicted)
color :white to off-white
Merck :14,9747
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :DFBIRQPKNDILPW-CIVMWXNOSA-N
CAS DataBase Reference :38748-32-2(CAS DataBase Reference)
EPA Substance Registry System :Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)- (38748-32-2)
alpha :D25 -154°
Boiling point :412.43°C (rough estimate)
Density :1.1656 (rough estimate)
refractive index :1.4450 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :solid
pka :14.25±0.60(Predicted)
color :white to off-white
Merck :14,9747
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :DFBIRQPKNDILPW-CIVMWXNOSA-N
CAS DataBase Reference :38748-32-2(CAS DataBase Reference)
EPA Substance Registry System :Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)- (38748-32-2)
Safety Information
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| Signal word: | Danger | ||||||||||||
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Description
Triptolide is the major bioactive constituent of T. wilfordii Hook F., also known as thunder god vine, a traditional Chinese medicinal herb with known antiproliferative, immunosuppressive, anti-inflammatory, antifertility, and anti-polycystic kidney disease effects. Triptolide binds to and inhibits human dCTP pyrophosphatase 1, a “gatekeeper” enzyme that prevents deleterious halogenated nucleotides from entering DNA synthesis, with a Ki value of 168 μM and an IC50 value of 7-10 nM. Triptolide has also been shown to inhibit LPS-stimulated induction of cyclooxygenase 2 mRNA and synthesis of prostaglandin E2 in human peripheral blood monocytes, rheumatoid arthritis synovial fibroblasts, and human neonatal foreskin fibroblasts with an IC50 value of 0.04 μM.More related product prices
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