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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >DROXIDOPA

DROXIDOPA

DROXIDOPA Structure
  • ₹8000 - ₹58390.05
  • Product name: DROXIDOPA
  • CAS: 23651-95-8
  • MF: C9H11NO5
  • MW: 213.19
  • EINECS:
  • MDL Number:MFCD00799030
  • Synonyms:L-threo-b-(3,4-Dihydroxyphenyl)serine;L-Tyrosine, b,3-dihydroxy-, threo-;L-Tyrosine, β,3-dihydroxy-, (βR)-;Serine, 3-(3,4-dihydroxyphenyl)-, L-threo- (8CI);SM 5688;threo-Dopaserine;(2S,3R)-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic acid;(βR)-β,3-Dihydroxy-L-tyrosine
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 50MG
  • 200MG
  • ManufacturerTCI Chemicals (India)
  • Product numberD4235
  • Product descriptionDroxidopa
  • Packaging50MG
  • Price₹8000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4235
  • Product descriptionDroxidopa
  • Packaging200MG
  • Price₹24000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9446
  • Product descriptionL-DOPS ≥98% (HPLC)
  • Packaging5MG
  • Price₹14451.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9446
  • Product descriptionL-DOPS ≥98% (HPLC)
  • Packaging25MG
  • Price₹58390.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4235 Droxidopa 50MG ₹8000 2022-05-26 Buy
TCI Chemicals (India) D4235 Droxidopa 200MG ₹24000 2022-05-26 Buy
Sigma-Aldrich(India) D9446 L-DOPS ≥98% (HPLC) 5MG ₹14451.38 2022-06-14 Buy
Sigma-Aldrich(India) D9446 L-DOPS ≥98% (HPLC) 25MG ₹58390.05 2022-06-14 Buy

Properties

Melting point :232-235° (dec); mp 229-232° (dec) (Ohashi)
alpha :D20 -39° (c = 1 in 1N aq HCl); D20 -42.0° (c = 1 in 1N aq HCl)
Boiling point :549.8±50.0 °C(Predicted)
Density :1.608±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: ≥3mg/mL
pka :2.09±0.24(Predicted)
form :powder
color :white to tan
Merck :14,3457
Stability :Hygroscopic
CAS DataBase Reference :23651-95-8

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Droxidopa is a synthetic amino acid precursor of (-)-norepinephrine which is absorbed from the gut and metabolized to norepinephrine. In Parkinsonian patients, droxidopa added to existing levodopa/decarboxylase inhibitor therapy produces significant improvements in retropulsion, dysarthria and muscular rigidity refractory to other treatments; however, tremor was unaffected.

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