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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cytoskeletal Signaling >Dynamin inhibitors >Dynasore

Dynasore

Dynasore Structure
  • ₹5500 - ₹11300
  • Product name: Dynasore
  • CAS: 304448-55-3
  • MF: C18H14N2O4
  • MW: 322.31
  • EINECS:200-256-5
  • MDL Number:MFCD00292551
  • Synonyms:(E)-N'-(3,4-DIHYDROXYBENZYLIDENE)-3-HYDROXY-2-NAPHTHOHYDRAZIDE;2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(3,4-dihydroxyphenyl)methylene]hydrazide;3-Hydroxy-2-naphthalenecarboxylic acid [(3,4-dihydroxyphenyl)methylene]hydrazide Dynasore;Dynasore, >=98%;(E)-3-Hydroxy-N'-((3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl)-2-naphthohydrazide;Dynamin Inhibitor I, Dynasore;N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide;N'-[(E)-(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberD5461
  • Product descriptionDynasore
  • Packaging10MG
  • Price₹5500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD5461
  • Product descriptionDynasore
  • Packaging50MG
  • Price₹11300
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number324410
  • Product descriptionDynamin Inhibitor I, Dynasore - CAS 304448-55-3 - Calbiochem The Dynamin Inhibitor I, Dynasore, also referenced under CAS 304448-55-3, controls the biological activity of Dynamin. This small molecule/inhibitor i
  • Packaging10MG
  • Price₹9490
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D5461 Dynasore 10MG ₹5500 2022-05-26 Buy
TCI Chemicals (India) D5461 Dynasore 50MG ₹11300 2022-05-26 Buy
Sigma-Aldrich(India) 324410 Dynamin Inhibitor I, Dynasore - CAS 304448-55-3 - Calbiochem The Dynamin Inhibitor I, Dynasore, also referenced under CAS 304448-55-3, controls the biological activity of Dynamin. This small molecule/inhibitor i 10MG ₹9490 2022-06-14 Buy

Properties

Melting point :>224°C (dec.)
Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 1 mg/ml).
form :Off-white solid.
pka :8.49±0.35(Predicted)
color :Beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
CAS DataBase Reference :304448-55-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Dynasore is a cell-permeable, reversible inhibitor of dynamin 1, dynamin 2, and mitochondrial dynamin, Drp1 GTPase activity (IC50 = 15 μM). Through this action, dynasore inhibits clathrin-dependent vesicle formation and endocytosis, which is necessary for internalization of certain parasites and viruses, as well as particles and receptor ligands. In some cases, dynasore can also augment the release of neurotransmitters and secreted cytokines.

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