Esculetin
6 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 50MG
- 200MG
- 1G
- 5G
- ManufacturerTCI Chemicals (India)
- Product numberE1287
- Product descriptionEsculetin [Matrix for MALDI-TOF/MS]
- Packaging200MG
- Price₹2700
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberE0386
- Product descriptionEsculetin
- Packaging1G
- Price₹3100
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberE1287
- Product descriptionEsculetin [Matrix for MALDI-TOF/MS]
- Packaging1G
- Price₹7800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number246573
- Product description6,7-Dihydroxycoumarin 98%
- Packaging1G
- Price₹2749.55
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number68923
- Product descriptionEsculetin analytical standard
- Packaging50MG
- Price₹5585.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number246573
- Product description6,7-Dihydroxycoumarin 98%
- Packaging5G
- Price₹11701.83
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | E1287 | Esculetin [Matrix for MALDI-TOF/MS] | 200MG | ₹2700 | 2022-05-26 | Buy |
TCI Chemicals (India) | E0386 | Esculetin | 1G | ₹3100 | 2022-05-26 | Buy |
TCI Chemicals (India) | E1287 | Esculetin [Matrix for MALDI-TOF/MS] | 1G | ₹7800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | 246573 | 6,7-Dihydroxycoumarin 98% | 1G | ₹2749.55 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 68923 | Esculetin analytical standard | 50MG | ₹5585.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 246573 | 6,7-Dihydroxycoumarin 98% | 5G | ₹11701.83 | 2022-06-14 | Buy |
Properties
Melting point :271-273 °C(lit.)
Boiling point :270.35°C (rough estimate)
Density :1.3431 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :2-8°C
solubility :Solubility Almost insoluble in boiling water, ether; soluble in hot ethanol, glacial acetic acid
form :powder
pka :1.71(at 25℃)
color :Light yellow
PH Range :Weak blue uorescence (1.5) to strong blue uorescence (2.0)
Water Solubility :slightly soluble
Merck :14,3697
BRN :152788
Major Application :antiinflammatory, Herbicides, cosmetics, teeth whitening agent, antifungal, neurodegenerative andfungal, antibacterial, antiviral, treating drug-induced weight gain, neurodegenerative and blood coagulation disorders, cancer, amyloidosis, skin impairments and baldness
InChIKey :ILEDWLMCKZNDJK-UHFFFAOYSA-N
LogP :0.980 (est)
CAS DataBase Reference :305-01-1(CAS DataBase Reference)
NIST Chemistry Reference :Coumarin, 6,7-dihydroxy-(305-01-1)
EPA Substance Registry System :Esculetin (305-01-1)
Boiling point :270.35°C (rough estimate)
Density :1.3431 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :2-8°C
solubility :Solubility Almost insoluble in boiling water, ether; soluble in hot ethanol, glacial acetic acid
form :powder
pka :1.71(at 25℃)
color :Light yellow
PH Range :Weak blue uorescence (1.5) to strong blue uorescence (2.0)
Water Solubility :slightly soluble
Merck :14,3697
BRN :152788
Major Application :antiinflammatory, Herbicides, cosmetics, teeth whitening agent, antifungal, neurodegenerative andfungal, antibacterial, antiviral, treating drug-induced weight gain, neurodegenerative and blood coagulation disorders, cancer, amyloidosis, skin impairments and baldness
InChIKey :ILEDWLMCKZNDJK-UHFFFAOYSA-N
LogP :0.980 (est)
CAS DataBase Reference :305-01-1(CAS DataBase Reference)
NIST Chemistry Reference :Coumarin, 6,7-dihydroxy-(305-01-1)
EPA Substance Registry System :Esculetin (305-01-1)
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
In the presence of esculetin and HA14-1 (sc-205911) expression of the death receptor 4 (DR4) has been observed to be upregulated and extracellular-regulated kinase (ERK) to be activated. Other studies suggest that esculetin upregulates death receptor 5 (DR5) protein expression, and enhances TRAIL-induced apoptosis. It also inhibits the activity of 12-LO (12-lipoxygenase), and decreases leukotriene biosynthesis during 5-LO inhibition.More related product prices
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