GANAXOLONE
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- ₹15349.85 - ₹62319.53
- Product name: GANAXOLONE
- CAS: 38398-32-2
- MF: C22H36O2
- MW: 332.52
- EINECS:
- MDL Number:MFCD09971088
- Synonyms:3α-hydroxy-3β-methyl-5α-pregnan-20-one;(3α,5α)-3-Hydroxy-3-methyl-pregnan-20-one;1-((3R,5S,8R,9S,10S,13S,14S,17S)-3-Hydroxy-3,10,13-trimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone;(3α,5α)-3-Hydroxy-3-methylpregnan-20-one;1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone;Pregnan-20-one, 3-hydroxy-3-methyl-, (3α,5α)-;Fampridine Impurity 80;5α-PREGNAN-3β-METHYL-3α-OL-20-ONE
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberG7795
- Product descriptionGanaxolone solid
- Packaging5MG
- Price₹15349.85
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG7795
- Product descriptionGanaxolone solid
- Packaging25MG
- Price₹62319.53
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G7795 | Ganaxolone solid | 5MG | ₹15349.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G7795 | Ganaxolone solid | 25MG | ₹62319.53 | 2022-06-14 | Buy |
Properties
Melting point :190-192°
alpha :D +103°
Boiling point :434.8±18.0 °C(Predicted)
Density :1.036±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~4.2 mg/mL
form :solid
pka :15.18±0.70(Predicted)
color :white
alpha :D +103°
Boiling point :434.8±18.0 °C(Predicted)
Density :1.036±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~4.2 mg/mL
form :solid
pka :15.18±0.70(Predicted)
color :white
Safety Information
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| Signal word: | Warning | |||||||
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Description
Ganaxolone is a synthetic neurosteroid which functions as a stereoselective modulator of GABAA receptors. Studies indicate that ganaxolone enhances GABA-evoked chloride currents in Xenopus oocytes. It is known that the compound modulates GABAA receptors by inhibiting GABAA receptor-chloride channel ligand binding and enhancing ligand binding at the benzodiazepine site. Alternatively, ganaxolone increases serotonergic neuron firing in rats after 3 to 7 days. Studies conducted on animal seizure models demonstrate that ganaxolone displays anticonvulsant effects. Furthermore, ganaxolone suppresses seizures in mice induced by maximal electroshock (ED50 of 29.7 mg/kg i.p.).More related product prices
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