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ChemicalBook > Product Catalogue >API >Inhibitors >GW-501516

GW-501516

GW-501516 Structure
  • ₹10684.28 - ₹43505.68
  • Product name: GW-501516
  • CAS: 317318-70-0
  • MF: C21H18F3NO3S2
  • MW: 453.5
  • EINECS:1592732-453-0
  • MDL Number:MFCD09033000
  • Synonyms:2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]methylsulfanyl]phenoxy]acetic acid;GW 501516, >=98%;ENDUROBOL (GW-501516)/CARDARINE/;Cardarine(GW501516, GSK-516);GW-501615;2-(4-((2-(4-(Trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylthio)-2-methylphenoxy)acetic a;{2-Methyl-4-[4-Methyl-2-(4-trifluoroMethyl-phenyl)-thiazol-5-ylMethylsulfanyl]-phenoxy}-acetic acid;Aceticacid, [2-Methyl-4-[[[4-Methyl-2-[4-(trifluoroMethyl)phenyl]-5-thiazolyl]Methyl]thio]phenoxy]-(9CI)
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1491
  • Product descriptionGW501516 ≥98% (HPLC)
  • Packaging5MG
  • Price₹10684.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number43732
  • Product description{2-Methyl-4-{{4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl}methylthio}phenoxy}acetic acid analytical standard
  • Packaging25MG
  • Price₹21087.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1491
  • Product descriptionGW501516 ≥98% (HPLC)
  • Packaging25MG
  • Price₹43505.68
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1491 GW501516 ≥98% (HPLC) 5MG ₹10684.28 2022-06-14 Buy
Sigma-Aldrich(India) 43732 {2-Methyl-4-{{4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl}methylthio}phenoxy}acetic acid analytical standard 25MG ₹21087.1 2022-06-14 Buy
Sigma-Aldrich(India) SML1491 GW501516 ≥98% (HPLC) 25MG ₹43505.68 2022-06-14 Buy

Properties

Melting point :134-136°C
Boiling point :584.5±60.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :3.17±0.10(Predicted)
color :white to beige
BRN :18515150
Stability :Light Sensitive
InChI :InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26,27)
InChIKey :YDBLKRPLXZNVNB-UHFFFAOYSA-N
SMILES :C(O)(=O)COC1=CC=C(SCC2SC(C3=CC=C(C(F)(F)F)C=C3)=NC=2C)C=C1C
CAS DataBase Reference :317318-70-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes. Studies demonstrate that GW501516 can regulate expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells. Additionally, GW501516 has been shown to block insulin resistance and fatty acid-induced nuclear factor-κB (NF-κB) activation.

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Suppliers and manufacturers

Shenzhen Wolid Technology Co., Ltd.
GW1516(Cardarine)
₹1.00 /1kg
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Wuhan Cell Pharmaceutical Co., Ltd
GW501516（Cardarine）
₹9.90 /1g
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Shanghai Getian Industrial Co., LTD
GW-501516
₹24.00 /1box
GW-501516 CAS:317318-70-0
CHEMSWORTH CLEARSYNTH LABS LTD. A.J Chemicals SynZeal Research Pvt Ltd
Shanghai Longyu Biotechnology Co., Ltd.
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
Zhejiang J&C Biological Technology Co.,Limited