Harpagoside
- ₹14202.4
- Product name: Harpagoside
- CAS: 19210-12-9
- MF: C24H30O11
- MW: 494.49
- EINECS:242-881-6
- MDL Number:MFCD00017415
- Synonyms:HARPAGOSIDE;Harpagosid;[1S-[1alpha,4aalpha,5alpha,7alpha(E),7aalpha]]-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(allyl-1-oxo-3-phenyl)oxy]cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside;[(1S,4aS,5R,7S,7aS)-4a,5-Dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate;HARPAGOSIDE WITH HPLC;7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl;β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6;8-O-E CINNAMOYL HARPAGIDE
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Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- ManufacturerSigma-Aldrich(India)
- Product number68527
- Product descriptionHarpagoside analytical standard
- Packaging10MG
- Price₹14202.4
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 68527 | Harpagoside analytical standard | 10MG | ₹14202.4 | 2022-06-14 | Buy |
Properties
Melting point :120°C (dec.)
Boiling point :720.7±60.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :11.70±0.70(Predicted)
form :Solid
color :White to Light Yellow
Stability :Hygroscopic
InChIKey :KVRQGMOSZKPBNS-FMHLWDFHSA-N
LogP :-1.591 (est)
CAS DataBase Reference :19210-12-9(CAS DataBase Reference)
Boiling point :720.7±60.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :11.70±0.70(Predicted)
form :Solid
color :White to Light Yellow
Stability :Hygroscopic
InChIKey :KVRQGMOSZKPBNS-FMHLWDFHSA-N
LogP :-1.591 (est)
CAS DataBase Reference :19210-12-9(CAS DataBase Reference)
Safety Information
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Description
Harpagoside is an anti-inflammatory small molecule natural product originally isolated from the Harpagophytum procumbens (Devil’s Claw) root, but can be isolated from other plants such as Crophularia ningpoensis Hemsl (Figwort). Treatment of HepG2 cells with Harpagoside demonstrated suppression of NF-κB nuclear translocation and degradation of IκB-α, blocking NF-κB activation. Multiple anti-inflammatory cellular effects were correlated with this blockade, as Harpagoside was observed to inhibit the expression of inflammation-mediating enzymes cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and to reduce lipopolysaccharide-induced mRNA levels. The suppression of NF-κB activation is indicated as the mechanism beneath the anti-inflammatory effects of Harpagoside.More related product prices
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Suppliers and manufacturers
A.J Chemicals
CLEARSYNTH LABS LTD.
Pharma Affiliates
Pharmaffiliates Analytics and Synthetics P. Ltd
Chengdu Greenpure Biopharma CO.,Ltd