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ChemicalBook > Product Catalogue >API >Nervous system drugs >Drug Metabolism in Human Brain >Idebenone

Idebenone

Idebenone Structure
  • ₹4800 - ₹50379.55
  • Product name: Idebenone
  • CAS: 58186-27-9
  • MF: C19H30O5
  • MW: 338.44
  • EINECS:1308068-626-2
  • MDL Number:MFCD00274552
  • Synonyms:cv 2619 idebenone;Daruma:Mnesis;2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-;6-(10-Hydroxydecyl)ubiquinone;2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione;2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone;IDEBENONE(P);2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadienPl,4-dione
6 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • 100MG
  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberI0848
  • Product descriptionIdebenone
  • Packaging1G
  • Price₹4800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0848
  • Product descriptionIdebenone
  • Packaging5G
  • Price₹9700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0848
  • Product descriptionIdebenone
  • Packaging25G
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number67805
  • Product descriptionIdebenone analytical standard
  • Packaging10MG
  • Price₹8486.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI5659
  • Product descriptionIdebenone ≥98% (HPLC)
  • Packaging25MG
  • Price₹15046.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI5659
  • Product descriptionIdebenone ≥98% (HPLC)
  • Packaging100MG
  • Price₹50379.55
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I0848 Idebenone 1G ₹4800 2022-05-26 Buy
TCI Chemicals (India) I0848 Idebenone 5G ₹9700 2022-05-26 Buy
TCI Chemicals (India) I0848 Idebenone 25G ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) 67805 Idebenone analytical standard 10MG ₹8486.8 2022-06-14 Buy
Sigma-Aldrich(India) I5659 Idebenone ≥98% (HPLC) 25MG ₹15046.75 2022-06-14 Buy
Sigma-Aldrich(India) I5659 Idebenone ≥98% (HPLC) 100MG ₹50379.55 2022-06-14 Buy

Properties

Melting point :52-550C
Boiling point :497.3±45.0 °C(Predicted)
Density :1.08±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :Soluble in DMSO (up to 25 mg/ml).
form :Solid
pka :15.20±0.10(Predicted)
color :Orange
Merck :14,4888
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChIKey :JGPMMRGNQUBGND-UHFFFAOYSA-N
SMILES :C1(=O)C(OC)=C(OC)C(=O)C(C)=C1CCCCCCCCCCO
LogP :3.490 (est)
CAS DataBase Reference :58186-27-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Idebenone is an organic compound belonging to the quinone family, being similar to coenzyme Q-10. It is a kind of drug developed by Takeda Pharmaceutical Company for the treatment of Alzheimer’s disease and some other cognitive defects. However, these have been not very much progress associated with this indication. It is now also used for the treatment of Friedreich’s ataxia with a positive effect on cardiac hypertrophy and neurological function. However, this indication is only approved in Canada, not in Europe and US. It is now under investigation on its efficacy for the treatment of Duchenne muscular dystrophy, Leber’s hereditary optic neuropathy, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) as well as primary progressive multiple sclerosis. The efficacy of this drug still demands more evidences.

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