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IDRA 21

IDRA 21 Structure
  • ₹24183.05
  • Product name: IDRA 21
  • CAS: 22503-72-6
  • MF: C8H9ClN2O2S
  • MW: 232.69
  • EINECS:1592732-453-0
  • MDL Number:MFCD00270874
  • Synonyms:IDRA 21;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE S,S-DIOXIDE;IDRA 21,98%;7-chloro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide;7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide;2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-Methyl-, 1,1-dioxide
1 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberI5773
  • Product descriptionIDRA 21 ≥98%
  • Packaging5MG
  • Price₹24183.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) I5773 IDRA 21 ≥98% 5MG ₹24183.05 2022-06-14 Buy

Properties

Melting point :209 °C(Solv: acetic acid (64-19-7))
Boiling point :405.1±55.0 °C(Predicted)
Density :1.394±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :9.78±0.40(Predicted)
color :Off-White to Pale Yellow
InChIKey :VZRNTCHTJRLTMU-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

IDRA-21 is a benzothiadiazine derivative and a positive allosteric modulator of glutamate AMPA receptors (1,2,3,4). It is able to increase excitatory synaptic strength by inhibiting AMPA receptor desensitization. IDRA 21 may exhibit therapeutic effects to ameliorate memory deficits in patients with cognitive impairments such as Alzheimer''s disease.

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