kaurenoic acid
- ₹44328.38
- Product name: kaurenoic acid
- CAS: 6730-83-2
- MF: C20H30O2
- MW: 302.45
- EINECS:
- MDL Number:MFCD28978039
- Synonyms:kaurenoic acid;(-)-Kaur-16-en-18-oic acid;Cunabic acid;Kaurane-16-ene-18-oic acid;ent-Kaur-16(17)-en-19-oic acid;ent-Kaur-16-en-19-oic acid;NSC 339145;Kaur-16-en-18-oic acid,(4a)-
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- ManufacturerSigma-Aldrich(India)
- Product numberSMB00177
- Product descriptionKaurenoic acid ≥95% (LC/MS-ELSD)
- Packaging1MG
- Price₹44328.38
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SMB00177 | Kaurenoic acid ≥95% (LC/MS-ELSD) | 1MG | ₹44328.38 | 2022-06-14 | Buy |
Properties
Melting point :171-172 °C
Boiling point :426.6±34.0 °C(Predicted)
Density :1.10±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMF: 10 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 10 mg/ml
form :A solid
pka :4.70±0.40(Predicted)
color :White to off-white
Boiling point :426.6±34.0 °C(Predicted)
Density :1.10±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMF: 10 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 10 mg/ml
form :A solid
pka :4.70±0.40(Predicted)
color :White to off-white
Safety Information
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Description
Kaurenoic acid is a diterpene that has been found in C. langsdorffii and has diverse biological activities, including anticancer, antibacterial, antioxidant, and anti-inflammatory properties. It is cytotoxic to 22Rv1 and LNCaP prostate, HT-29, HCT116, SW480, and SW620 colon, and MCF-7 breast cancer cells with IC50 values ranging from 15.03 to 48.87 μg/ml. Kaurenoic acid is active against S. epidermidis, S. capitis, E. faecalis, and S. haemolyticus in vitro (MICs = 6.25-12.5 μg/ml). Kaurenoic acid (50 and 100 mg/kg) reduces colonic myeloperoxidase (MPO) activity and malondialdehyde (MDA) levels in a rat model of acetic acid-induced colitis, as well as colonic tissue damage, leukocytic infiltration, and submucosal edema when administered at a dose of 100 mg/kg.More related product prices
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