Maraviroc
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- ₹15458.1 - ₹62081.38
- Product name: Maraviroc
- CAS: 376348-65-1
- MF: C29H41F2N5O
- MW: 513.68
- EINECS:609-456-0
- MDL Number:MFCD09953791
- Synonyms:Maraviroc;Maraviroc(UK427857);4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide;UK-427857; CELSENTRI;CS-49;maroviroc;4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide;Maraviroc(Selzentry)
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0002
- Product descriptionMaraviroc ≥98% (HPLC)
- Packaging25MG
- Price₹62081.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPZ0002
- Product descriptionMaraviroc ≥98% (HPLC)
- Packaging5MG
- Price₹15458.1
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PZ0002 | Maraviroc ≥98% (HPLC) | 25MG | ₹62081.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PZ0002 | Maraviroc ≥98% (HPLC) | 5MG | ₹15458.1 | 2022-06-14 | Buy |
Properties
Melting point :79-81°C
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >30mg/mL
pka :7.3(at 25℃)
form :white powder
color :White
optical activity :[α]-15/D
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25-,26-/s3
InChIKey :GSNHKUDZZFZSJB-RWJISDSDNA-N
SMILES :C(N1[C@@H]2CC[C@H]1C[C@H](N1C(=NN=C1C(C)C)C)C2)C[C@@H](C1C=CC=CC=1)NC(C1CCC(F)(F)CC1)=O |&1:2,5,7,19,r|
CAS DataBase Reference :376348-65-1(CAS DataBase Reference)
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >30mg/mL
pka :7.3(at 25℃)
form :white powder
color :White
optical activity :[α]-15/D
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25-,26-/s3
InChIKey :GSNHKUDZZFZSJB-RWJISDSDNA-N
SMILES :C(N1[C@@H]2CC[C@H]1C[C@H](N1C(=NN=C1C(C)C)C)C2)C[C@@H](C1C=CC=CC=1)NC(C1CCC(F)(F)CC1)=O |&1:2,5,7,19,r|
CAS DataBase Reference :376348-65-1(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Maraviroc is an antagonist of the C-C chemokine receptor type 5 (CCR5), inhibiting binding of the ligand RANTES with an IC50 value of 1.4 nM. Because human immunodeficiency virus (HIV) uses CCR5 to enter monocytes and macrophages, maraviroc inhibits HIV-1 replication in CCR5-expressing cells (IC50 = 2.8 nM). The pharmacokinetics of maraviroc in healthy male subjects have been delineated.More related product prices
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