Methotrexate
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- ₹8738.1 - ₹13960
- Product name: Methotrexate
- CAS: 59-05-2
- MF: C20H22N8O5
- MW: 454.45
- EINECS:200-413-8
- MDL Number:MFCD00064370
- Synonyms:METHOTREXATEFORINJECTION;METHOTREXATE(N-(4-(((2,4-DIAMINO-6-PTERIDINYL)METHYLAMINO)BENZOYL)-L-GLUTAMICACID);4-Amino-N10-methylfolic acid;Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)- (8CI);L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI);L-Methotrexate;Methotrexat-Ebewe;METHOTREXATEC
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 100MG
- 1ML
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberM-136
- Product descriptionMethotrexate solution 1.0?mg/mL in methanol with 0.1N NaOH, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹8738.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1396
- Product descriptionMethotrexate Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹9894.05
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number454126
- Product descriptionMethotrexate - CAS 59-05-2 - Calbiochem
- Packaging100MG
- Price₹13960
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | M-136 | Methotrexate solution 1.0?mg/mL in methanol with 0.1N NaOH, ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹8738.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1396 | Methotrexate Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹9894.05 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 454126 | Methotrexate - CAS 59-05-2 - Calbiochem | 100MG | ₹13960 | 2022-06-14 | Buy |
Properties
Melting point :195°C
Boiling point :561.26°C (rough estimate)
alpha :+17~+24°(D/20℃)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis)
Density :1.4080 (rough estimate)
refractive index :1.6910 (estimate)
Flash point :11℃
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: insoluble
form :powder
pka :pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain)
color :Light yellow to yellow
Water Solubility :Insoluble. <0.1 g/100 mL at 19 ºC
Sensitive :Light Sensitive & Hygroscopic
Merck :14,5985
BRN :70669
BCS Class :3
Stability :Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below.
InChIKey :FBOZXECLQNJBKD-ZDUSSCGKSA-N
CAS DataBase Reference :59-05-2(CAS DataBase Reference)
NIST Chemistry Reference :Methotrexate(59-05-2)
IARC :3 (Vol. 26, Sup 7) 1987
EPA Substance Registry System :Methotrexate (59-05-2)
Boiling point :561.26°C (rough estimate)
alpha :+17~+24°(D/20℃)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis)
Density :1.4080 (rough estimate)
refractive index :1.6910 (estimate)
Flash point :11℃
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: insoluble
form :powder
pka :pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain)
color :Light yellow to yellow
Water Solubility :Insoluble. <0.1 g/100 mL at 19 ºC
Sensitive :Light Sensitive & Hygroscopic
Merck :14,5985
BRN :70669
BCS Class :3
Stability :Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below.
InChIKey :FBOZXECLQNJBKD-ZDUSSCGKSA-N
CAS DataBase Reference :59-05-2(CAS DataBase Reference)
NIST Chemistry Reference :Methotrexate(59-05-2)
IARC :3 (Vol. 26, Sup 7) 1987
EPA Substance Registry System :Methotrexate (59-05-2)
Safety Information
Symbol(GHS): |
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Description
Methotrexate (MTX) is an analog of folic acid and aminopterin that is used in the treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid and blocking key enzymes in the synthesis of purines and pyrimidines required for cell proliferation. MTX is known to induce adenosine release, which mediates many of its anti-inflammatory effects including the reduction of proinflammatory cytokines. MTX is still considered the gold standard of DMARD (disease-modifying antirheumatic drug) therapy to treat both the immune-inflammatory and joint destructive processes of rheumatoid arthritis.More related product prices
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