Milrinone
- ₹4900 - ₹96180.13
- Product name: Milrinone
- CAS: 78415-72-2
- MF: C12H9N3O
- MW: 211.22
- EINECS:278-903-6
- MDL Number:MFCD00133539
- Synonyms:Corotrope;Milrila;3-CYANO-6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE;6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE-3-CARBONITRILE;1,6-DIHYDRO-2-METHYL-6-OXO-(3,4'-BIPYRIDINE)-5-CARBONITRILE;6-Methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile;YM-018;2-Oxo-5-(4-pyridyl)-6-methyl-1,2-dihydropyridine-3-carbonitrile
8 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
- ottokemi
Package
- 10MG
- 50MG
- 100MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberM1663
- Product descriptionMilrinone
- Packaging100MG
- Price₹4900
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberM1663
- Product descriptionMilrinone
- Packaging1G
- Price₹17400
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM4659
- Product descriptionMilrinone ≥97% (TLC), powder
- Packaging10MG
- Price₹24410.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number475840
- Product descriptionMilrinone - CAS 78415-72-2 - Calbiochem A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC?? = 300 nM).
- Packaging10MG
- Price₹27450.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR2515
- Product descriptionMilrinone Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹28361.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM4659
- Product descriptionMilrinone ≥97% (TLC), powder
- Packaging50MG
- Price₹96180.13
- Updated2022-06-14
- Buy
- Manufacturerottokemi
- Product number M 0699
- Product descriptionMilrinone, ≥98%
- Packaging10mg
- Price₹18909
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number M 0699
- Product descriptionMilrinone, ≥98%
- Packaging50mg
- Price₹74079
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | M1663 | Milrinone | 100MG | ₹4900 | 2022-05-26 | Buy |
TCI Chemicals (India) | M1663 | Milrinone | 1G | ₹17400 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | M4659 | Milrinone ≥97% (TLC), powder | 10MG | ₹24410.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 475840 | Milrinone - CAS 78415-72-2 - Calbiochem A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC?? = 300 nM). | 10MG | ₹27450.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR2515 | Milrinone Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹28361.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M4659 | Milrinone ≥97% (TLC), powder | 50MG | ₹96180.13 | 2022-06-14 | Buy |
ottokemi | M 0699 | Milrinone, ≥98% | 10mg | ₹18909 | 2022-05-26 | Buy |
ottokemi | M 0699 | Milrinone, ≥98% | 50mg | ₹74079 | 2022-05-26 | Buy |
Properties
Melting point :>3000C
Boiling point :350.9°C (rough estimate)
Density :1.1922 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :DMSO: >10 mg/mL
form :powder
pka :7.21±0.10(Predicted)
color :off-white
Water Solubility :Soluble in DMSO. Insoluble in water.
Merck :14,6197
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :FYEJSUDMDUIMKJ-UHFFFAOYSA-N
CAS DataBase Reference :78415-72-2(CAS DataBase Reference)
Boiling point :350.9°C (rough estimate)
Density :1.1922 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :DMSO: >10 mg/mL
form :powder
pka :7.21±0.10(Predicted)
color :off-white
Water Solubility :Soluble in DMSO. Insoluble in water.
Merck :14,6197
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :FYEJSUDMDUIMKJ-UHFFFAOYSA-N
CAS DataBase Reference :78415-72-2(CAS DataBase Reference)
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
Phosphodiesterase 3 (PDE3) family members have high-affinities for both cAMP and cGMP and show cGMP-dependent inhibition of cAMP hydrolysis. Milrinone is a potent inhibitor of type 3 phosphodiesterases (PDEs), inhibiting recombinant PDE3A and PDE3B with IC50 values of 0.45 and 1.0 μM, respectively. It less effectively inhibits other PDE isoforms, with IC50 values of 263, >300, 17.5, 49.1, and 58.3 μM for PDE1, PDE2, PDE4, PDE5, and PDE7, respectively. Milrinone has positive inotropic (stimulates cardiac muscle contractions) and vasodilatory effects when administered in vivo.More related product prices
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