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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Other antineoplastic Drugs >Mitotan

Mitotan

Mitotan Structure
  • ₹2400 - ₹8300
  • Product name: Mitotan
  • CAS: 53-19-0
  • MF: C14H10Cl4
  • MW: 320.04
  • EINECS:200-166-6
  • MDL Number:MFCD00000850
  • Synonyms:2,4’-dichlorophenyldichlorethane ;2,4'-Dichlorophenyldichlorethane;Benzene, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-;Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-;Ethane, 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloro-;ethane,2,2-dichloro-1-(2-chlorophenyl)-1-(4-chlorophenyl)- ;Khlodithan;NCI-C04933
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 250MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberM3304
  • Product descriptionMitotane min. 98.0 %
  • Packaging1G
  • Price₹2400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM3304
  • Product descriptionMitotane min. 98.0 %
  • Packaging5G
  • Price₹8300
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number35485
  • Product description2,4′-DDD PESTANAL?, analytical standard
  • Packaging250MG
  • Price₹7838.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1885
  • Product descriptionMitotane ≥98% (HPLC)
  • Packaging100MG
  • Price₹5260.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M3304 Mitotane min. 98.0 % 1G ₹2400 2022-05-26 Buy
TCI Chemicals (India) M3304 Mitotane min. 98.0 % 5G ₹8300 2022-05-26 Buy
Sigma-Aldrich(India) 35485 2,4′-DDD PESTANAL?, analytical standard 250MG ₹7838.65 2022-06-14 Buy
Sigma-Aldrich(India) SML1885 Mitotane ≥98% (HPLC) 100MG ₹5260.95 2022-06-14 Buy

Properties

Melting point :77-78 °C(lit.)
Boiling point :405.59°C (rough estimate)
Density :1.3118 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :white to beige
Water Solubility :<0.1 g/100 mL at 24 ºC
Merck :13,6237 / 13,6237
BRN :2056007
InChI :InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H
InChIKey :JWBOIMRXGHLCPP-UHFFFAOYSA-N
SMILES :C1(Cl)=CC=CC=C1C(C1=CC=C(Cl)C=C1)C(Cl)Cl
CAS DataBase Reference :53-19-0(CAS DataBase Reference)
NIST Chemistry Reference :Mitotane(53-19-0)
EPA Substance Registry System :o,p'-DDD (53-19-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Mitotane is an inhibitor of steroidogenesis that suppresses the growth of adrenocortical cells. It blocks the expression of several genes that encode proteins involved in steroidogenesis and disrupts mitochondrial respiratory chain activity in human adrenocortical cells. Mitotane has anti-neoplastic actions, alone or in combination with other compounds, and suppresses cortisol synthesis, although it also has significant toxicity in the gastrointestinal tract and nervous system. It is effective against adrenocortical carcinoma and Cushing’s Syndrome in clinical trials.

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Ethyl acrylate Ethyl acetate Benzene Etanol Ethylparaben 1,2-Dichloroethane HEXAFLUOROETHANE ETHANE Dichlorofluoroethane 1,1-DICHLOROETHANE CHLOROETHANE Mitotan

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Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
Mitotan
₹0.00 /25KG
Mitotan CAS:53-19-0
career henan chemical co
Mitotan
₹1.00 /1KG
Mitotan CAS: 53-19-0
TCI Chemicals (India) Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd CLEARSYNTH LABS LTD. Pharma Affiliates
Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd.
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED