MUSCIMOL
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- ₹10049.99 - ₹53269.83
- Product name: MUSCIMOL
- CAS: 2763-96-4
- MF: C4H6N2O2
- MW: 114.1
- EINECS:220-430-4
- MDL Number:MFCD00057894
- Synonyms:5-(aminomethyl)isoxazol-3-ol hydrate ;MUSCIMOL CRYSTALLINE;Containsupto10%Ethanol;5-Aminomethyl-3-hydroxyisoxazole, 5-(Aminomethyl)-3(2H)-isoxazolone;Muscimol: (5-Aminomethyl-3-isoxyzole);5-Aminomethylisoxazol-3(2H)-one;Muscimol hydrate,98%;Muscimol hydrate5-(Aminomethyl)-3-isoxazolol
4 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 10MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberM1523
- Product descriptionMuscimol powder
- Packaging25MG
- Price₹53269.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM1523
- Product descriptionMuscimol powder
- Packaging10MG
- Price₹24323.78
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM1523
- Product descriptionMuscimol powder
- Packaging5MG
- Price₹17049.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number5.06044
- Product descriptionMuscimol - CAS 2763-96-4 - Calbiochem Muscimol is a constituent and psychoactive ingredient of the mushroom Amanita muscaria, that acts as a potent agonist of GABAA receptors.
- Packaging1MG
- Price₹10049.99
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | M1523 | Muscimol powder | 25MG | ₹53269.83 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M1523 | Muscimol powder | 10MG | ₹24323.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M1523 | Muscimol powder | 5MG | ₹17049.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 5.06044 | Muscimol - CAS 2763-96-4 - Calbiochem Muscimol is a constituent and psychoactive ingredient of the mushroom Amanita muscaria, that acts as a potent agonist of GABAA receptors. | 1MG | ₹10049.99 | 2022-06-14 | Buy |
Properties
Melting point :175-176°C
Boiling point :213.59°C (rough estimate)
Density :1.291
refractive index :1.4487 (estimate)
storage temp. :2-8°C
solubility :ethanol: 1 mg/mL
pka :12.19±0.40(Predicted)
form :powder
color :white to off-white
Water Solubility :Soluble in water (10 mg/ml), methanol, ethanol, 0.05 M HCl (20 mg/ml), DMSO (sparingly soluble), DMF (sparingly soluble), and PBS (pH 7.2) (10 mg/ml).
Merck :13,6336
BRN :1618960
Stability :Hygroscopic, Store in Freezer at -20°C
EPA Substance Registry System :5-(Aminomethyl)-3-isoxazolol (2763-96-4)
Boiling point :213.59°C (rough estimate)
Density :1.291
refractive index :1.4487 (estimate)
storage temp. :2-8°C
solubility :ethanol: 1 mg/mL
pka :12.19±0.40(Predicted)
form :powder
color :white to off-white
Water Solubility :Soluble in water (10 mg/ml), methanol, ethanol, 0.05 M HCl (20 mg/ml), DMSO (sparingly soluble), DMF (sparingly soluble), and PBS (pH 7.2) (10 mg/ml).
Merck :13,6336
BRN :1618960
Stability :Hygroscopic, Store in Freezer at -20°C
EPA Substance Registry System :5-(Aminomethyl)-3-isoxazolol (2763-96-4)
Safety Information
Symbol(GHS): |
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Description
The amino acid γ-aminobutyric acid (GABA) is an inhibitory neurotransmitter that acts through two families of heteromeric ligand-gated ion channels, GABAA and GABAC and a G protein-coupled receptor, GABAB. Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity sites (Kd = 10 and 270 nM, respectively), stimulating chloride efflux with an EC50 value of 200 nM. Benzodiazepines enhance the effects of muscimol via GABAA without altering its binding. Muscimol activates GABAC receptors with an EC50 value of 1.3 μM. It also acts as an inhibitor of GABAA uptake and a substrate for the GABA-metabolizing enzyme GABA transaminase. Muscimol impairs memory formation and retrieval in mice and attenuates airway constriction in guinea pigs in vivo.Related product price
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