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veratramine

veratramine Structure
  • ₹4000 - ₹8200
  • Product name: veratramine
  • CAS: 60-70-8
  • MF: C27H39NO2
  • MW: 409.6
  • EINECS:
  • MDL Number:MFCD00468124
  • Synonyms:veratramine;Vreaframine;(3b,23b)-14,15,16,17-Teradehydroveratraman-3,23-diol;NSC 17821;NSC 2388;AIDS011940;(3,23)-14,15,16,17-Teradehydroveratraman-3,23-diol;NSC 23880
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 10MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberV0148
  • Product descriptionVeratramine
  • Packaging10MG
  • Price₹4000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberV0148
  • Product descriptionVeratramine
  • Packaging50MG
  • Price₹8200
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) V0148 Veratramine 10MG ₹4000 2022-05-26 Buy
TCI Chemicals (India) V0148 Veratramine 50MG ₹8200 2022-05-26 Buy

Properties

Melting point :122-1240C
alpha :D25 -71.8° (c = 1.21); D25 -70° (c = 1.56 in methanol)
Boiling point :529.83°C (rough estimate)
Density :1.0393 (rough estimate)
refractive index :1.6400 (estimate)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 12 mg/ml) or in Ethanol (up to 10 mg/ml)
form :solid
pka :14.82±0.60(Predicted)
color :Tan
λmax :268nm(lit.)
Merck :14,9952
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
CAS DataBase Reference :60-70-8

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The hedgehog (Hh) signaling pathway, which is blocked by cyclopamine , plays a key role in morphogenesis and has potential applications in the treatment of cancer. Veratramine, a teratogenic steroidal alkaloid isolated from the corn lily (Veratrum sp.), is an analog of cyclopamine that can inhibit the Hh signaling-dependent proliferation of NIH/3T3 cells at 8 μM. Additionally, veratramine has anti-thrombotic activity as it dose dependently inhibits platelet aggregation in rabbits ex vivo. While it may be most useful as a signal transduction inhibitor for treating tumors, veratramine also induces serotonin release and inhibits its re-uptake in the CNS.

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