Mycophenolic acid
- ₹7000 - ₹41350
- Product name: Mycophenolic acid
- CAS: 24280-93-1
- MF: C17H20O6
- MW: 320.34
- EINECS:246-119-3
- MDL Number:MFCD00036814
- Synonyms:6-[4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-5-PHTHALANYL]-4-METHYL-4-HEXENOIC ACID;4-methyl-5-methoxy-7-hydroxy-6-(5-carboxy-3-methylpent-2-en-1-yl)-phthalide ;6-(5-carboxy-3-methyl-2-pentenyl)-7-hydroxy-5-methoxy-4-methyl-phthalid ;lilly-68618 ;(E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid;68618;Micophenolic acid;Mycophenolic acid,6-(1,3-Dihydro-7-hydroxy-5-methoxy-4-methyl-1-oxoisobenzofuran-6-yl)-4-methyl-4-hexanoic acid, 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
9 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 100MG
- 250MG
- 500MG
- 1G
- 1ML
- ManufacturerTCI Chemicals (India)
- Product numberM2216
- Product descriptionMycophenolic Acid
- Packaging1G
- Price₹7000
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM5255
- Product descriptionMycophenolic acid ≥98%
- Packaging50MG
- Price₹8779.08
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number89287
- Product descriptionMycophenolic acid analytical standard
- Packaging10MG
- Price₹9883.23
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM3536
- Product descriptionMycophenolic acid powder, BioReagent, suitable for cell culture
- Packaging50MG
- Price₹10446.13
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number475913
- Product descriptionMycophenolic Acid - CAS 24280-93-1 - Calbiochem An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the fo
- Packaging100MG
- Price₹12940
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM-106
- Product descriptionMycophenolic acid solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹24019.8
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM5255
- Product descriptionMycophenolic acid ≥98%
- Packaging250MG
- Price₹31738.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM3536
- Product descriptionMycophenolic acid powder, BioReagent, suitable for cell culture
- Packaging250MG
- Price₹35928.18
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number475913
- Product descriptionMycophenolic Acid - CAS 24280-93-1 - Calbiochem An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the fo
- Packaging500MG
- Price₹41350
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | M2216 | Mycophenolic Acid | 1G | ₹7000 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | M5255 | Mycophenolic acid ≥98% | 50MG | ₹8779.08 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 89287 | Mycophenolic acid analytical standard | 10MG | ₹9883.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M3536 | Mycophenolic acid powder, BioReagent, suitable for cell culture | 50MG | ₹10446.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 475913 | Mycophenolic Acid - CAS 24280-93-1 - Calbiochem An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the fo | 100MG | ₹12940 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M-106 | Mycophenolic acid solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹24019.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M5255 | Mycophenolic acid ≥98% | 250MG | ₹31738.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M3536 | Mycophenolic acid powder, BioReagent, suitable for cell culture | 250MG | ₹35928.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 475913 | Mycophenolic Acid - CAS 24280-93-1 - Calbiochem An immunosuppressive agent that inhibits de novo purine nucleotide synthesis via inhibition of inosine monophosphate dehydrogenase and prevents the fo | 500MG | ₹41350 | 2022-06-14 | Buy |
Properties
Melting point :141°C
Boiling point :419.24°C (rough estimate)
Density :1.2300 (rough estimate)
vapor pressure :0Pa at 22℃
refractive index :1.5200 (estimate)
Flash point :2℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :methanol: 50 mg/mL, clear, colorless to faintly yellow
form :powder
pka :4.5(at 25℃)
color :white to white with yellow cast
Water Solubility :13mg/L(25 ºC)
Merck :14,6327
BRN :1295848
BCS Class :2?
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
LogP :-1.83-2.28 at 25℃ and pH5-9
Dissociation constant :4.58-8.05 at 22.5-25℃
CAS DataBase Reference :24280-93-1(CAS DataBase Reference)
EPA Substance Registry System :4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- (24280-93-1)
Boiling point :419.24°C (rough estimate)
Density :1.2300 (rough estimate)
vapor pressure :0Pa at 22℃
refractive index :1.5200 (estimate)
Flash point :2℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :methanol: 50 mg/mL, clear, colorless to faintly yellow
form :powder
pka :4.5(at 25℃)
color :white to white with yellow cast
Water Solubility :13mg/L(25 ºC)
Merck :14,6327
BRN :1295848
BCS Class :2?
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
LogP :-1.83-2.28 at 25℃ and pH5-9
Dissociation constant :4.58-8.05 at 22.5-25℃
CAS DataBase Reference :24280-93-1(CAS DataBase Reference)
EPA Substance Registry System :4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)- (24280-93-1)
Safety Information
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Description
Mycophenolic acid, less accurately called mycophenolate, is a compound derived from Penicillium stoloniferum and related species. It can reversibly inhibit inosine monophosphate dehydrogenase (IMPDH), the enzyme that controls the rate of synthesis of guanine monophosphate in the de novo pathway of purine synthesis used in the proliferation of B and T lymphocytes. Mycophenolic acid also has antibacterial, anticancer, antifungal, and antiviral activities. These powerful properties have been exploited in studies on organ transplant survival, anti-proliferative, rheumatoid arthritis, and psoriasis. It was initially marketed as the prodrug mycophenolate mofetil (MMF) to improve oral bioavailability. More recently, the salt mycophenolate sodium has also been introduced. Mycophenolate mofetil is marketed under the trade name CellCept and mycophenolate sodium as Myfortic.Discovered by an Italian medical scientist Bartolomeo Gosio in 1893, mycophenolic acid was the first antibiotic to be synthesised in pure and crystalline form. But its medical application was forgotten until two American scientists C.L. Alsberg and O.M. Black resynthesised it in 1912, and gave its chemical name. It was eventually found to be a broad-spectrum acting drug having antiviral, antifungal, antibacterial, anticancer, and antipsoriasis properties. The clinically usable drug Cellcept was developed by South African geneticist Anthony Allison and his wife Elsie M. Eugui. It was first approved by the US Food and Drug Administration on 3 May 1995 for use in kidney transplantation.
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