Nadifloxacin
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- ₹3900 - ₹31825.5
- Product name: Nadifloxacin
- CAS: 124858-35-1
- MF: C19H21FN2O4
- MW: 360.38
- EINECS:638-863-6
- MDL Number:MFCD00865081
- Synonyms:NDFX;Nadifiloxacin;NadifloxacinAPI;7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-Methyl-4-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13),6,8-tetraene-3-carboxylic acid;9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid;NADIFLOXACIN;9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid;Acuati
5 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 25MG
- 100MG
- 200MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberN0931
- Product descriptionNadifloxacin
- Packaging200MG
- Price₹3900
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberN0931
- Product descriptionNadifloxacin
- Packaging1G
- Price₹10400
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSMB00375
- Product descriptionNadifloxacin ≥98% (HPLC)
- Packaging1G
- Price₹31825.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberCDS021591
- Product descriptionNadifloxacin
- Packaging25MG
- Price₹6170.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSMB00375
- Product descriptionNadifloxacin ≥98% (HPLC)
- Packaging100MG
- Price₹5585.7
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | N0931 | Nadifloxacin | 200MG | ₹3900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | N0931 | Nadifloxacin | 1G | ₹10400 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SMB00375 | Nadifloxacin ≥98% (HPLC) | 1G | ₹31825.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | CDS021591 | Nadifloxacin | 25MG | ₹6170.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SMB00375 | Nadifloxacin ≥98% (HPLC) | 100MG | ₹5585.7 | 2022-06-14 | Buy |
Properties
Melting point :245-2470C (dec)
Boiling point :624.9±55.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Sparingly, Heated)
form :White to yellow crystalline solid.
pka :5.55±0.40(Predicted)
color :White to Off-White
biological source :synthetic (Organic)
Merck :14,6345
InChI :InChI=1S/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26)
InChIKey :JYJTVFIEFKZWCJ-UHFFFAOYSA-N
SMILES :C12=CC(F)=C(N3CCC(O)CC3)C3=C1N(C(C)CC3)C=C(C(O)=O)C2=O
CAS DataBase Reference :124858-35-1(CAS DataBase Reference)
Boiling point :624.9±55.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Sparingly, Heated)
form :White to yellow crystalline solid.
pka :5.55±0.40(Predicted)
color :White to Off-White
biological source :synthetic (Organic)
Merck :14,6345
InChI :InChI=1S/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26)
InChIKey :JYJTVFIEFKZWCJ-UHFFFAOYSA-N
SMILES :C12=CC(F)=C(N3CCC(O)CC3)C3=C1N(C(C)CC3)C=C(C(O)=O)C2=O
CAS DataBase Reference :124858-35-1(CAS DataBase Reference)
Safety Information
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Description
Nadifloxacin is a cell-permeable, synthetic, broad-spectrum fluoroquinolone antibiotic that inhibits the growth of both gram-positive and gram-negative microbes. Studies suggest that the mechanism of inhibition occurs by interfering with DNA replication. Specifically Nadifloxacin suppresses gram-positive bacterial growth by targeting topoisomerase IV and suppresses gram-negative bacteria by inhibiting Topo II (DNA gyrase), which both function to relax postive supercoils before DNA replication. Furthermore, Nadifloxacin can decrease superoxide radical anions such as O2- and OH-, produced by neutrophils.Related product price
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