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OKADAIC ACID

OKADAIC ACID Structure
  • ₹4471 - ₹148429.99
  • Product name: OKADAIC ACID
  • CAS: 78111-17-8
  • MF: C44H68O13
  • MW: 805
  • EINECS:616-589-8
  • MDL Number:MFCD00083455
  • Synonyms:1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(;Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1;OA;OKADAIC ACID, PROROCENTRUM CONCAVUM;35-Demethyldinophysistoxin 1;35-Demethyl-DTX 1;NSC 677083;9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
8 prices
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Brand

  • ALFA India
  • Sigma-Aldrich(India)

Package

  • 100μG
  • 0.1MG
  • 500μG
  • 25μG
  • 50μg
  • 100μg
  • 300μg
  • ManufacturerALFA India
  • Product numberALF-J60155-IAM
  • Product descriptionOkadaic acid, 98%
  • Packaging50μg
  • Price₹4471
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J60155-EXG
  • Product descriptionOkadaic acid, 98%
  • Packaging100μg
  • Price₹20342
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J60155-EXS
  • Product descriptionOkadaic acid, 98%
  • Packaging300μg
  • Price₹54995
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number495604
  • Product descriptionOkadaic Acid, Prorocentrum sp. - CAS 78111-17-8 - Calbiochem Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC?? = 10-15 nM) and 2A (IC?? = 0.1 nM).
  • Packaging25μG
  • Price₹11880.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO9381
  • Product descriptionOkadaic acid from Prorocentrum concavum 92-100% (HPLC)
  • Packaging25μG
  • Price₹32994.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number495604
  • Product descriptionOkadaic Acid, Prorocentrum sp. - CAS 78111-17-8 - Calbiochem Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC?? = 10-15 nM) and 2A (IC?? = 0.1 nM).
  • Packaging100μG
  • Price₹37040
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO9381
  • Product descriptionOkadaic acid from Prorocentrum concavum 92-100% (HPLC)
  • Packaging0.1MG
  • Price₹88483.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number495604
  • Product descriptionOkadaic Acid, Prorocentrum sp. - CAS 78111-17-8 - Calbiochem Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC?? = 10-15 nM) and 2A (IC?? = 0.1 nM).
  • Packaging500μG
  • Price₹148429.99
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J60155-IAM Okadaic acid, 98% 50μg ₹4471 2022-05-26 Buy
ALFA India ALF-J60155-EXG Okadaic acid, 98% 100μg ₹20342 2022-05-26 Buy
ALFA India ALF-J60155-EXS Okadaic acid, 98% 300μg ₹54995 2022-05-26 Buy
Sigma-Aldrich(India) 495604 Okadaic Acid, Prorocentrum sp. - CAS 78111-17-8 - Calbiochem Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC?? = 10-15 nM) and 2A (IC?? = 0.1 nM). 25μG ₹11880.01 2022-06-14 Buy
Sigma-Aldrich(India) O9381 Okadaic acid from Prorocentrum concavum 92-100% (HPLC) 25μG ₹32994.6 2022-06-14 Buy
Sigma-Aldrich(India) 495604 Okadaic Acid, Prorocentrum sp. - CAS 78111-17-8 - Calbiochem Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC?? = 10-15 nM) and 2A (IC?? = 0.1 nM). 100μG ₹37040 2022-06-14 Buy
Sigma-Aldrich(India) O9381 Okadaic acid from Prorocentrum concavum 92-100% (HPLC) 0.1MG ₹88483.55 2022-06-14 Buy
Sigma-Aldrich(India) 495604 Okadaic Acid, Prorocentrum sp. - CAS 78111-17-8 - Calbiochem Okadaic Acid, CAS 78111-17-8, is a highly potent inhibitor of protein phosphatase 1 (IC?? = 10-15 nM) and 2A (IC?? = 0.1 nM). 500μG ₹148429.99 2022-06-14 Buy

Properties

Melting point :164-166 °C
alpha :D20 +21° (c = 0.33 in CHCl3); D25 +25.4° (c = 0.24 in CHCl3)
Boiling point :672.95°C (rough estimate)
Density :1.0795 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: ≥1 mg/mL
form :translucent film
pka :3.87±0.16(Predicted)
color :translucent
Water Solubility :It is soluble in ethanol (25 mg/ml), DMSO (25 mg/ml), methanol (<1 mg/ml), chloroform, acetone, ethyl acetate, DMF, and dimethylsulfoxide. Insoluble in water, unless first dissolved in organic solvents, such as DMSO or ethanol.
Merck :13,6891
Stability :Stable. Light and heat-sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference :78111-17-8
EPA Substance Registry System :1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, .alpha,5-dihydroxy-.alpha.,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (.alpha.R,2S,5R,6R,8S)- (78111-17-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junctions, causes vasodilation and is a very potent tumor promoter. Okadaic acid is an extremely useful tool for studying cellular processes that are regulated by phosphorylation. It is shown to activate atypical protein kinase C in adipocytes.

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