PROADIFEN HYDROCHLORIDE
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- ₹13087.43 - ₹36826.65
- Product name: PROADIFEN HYDROCHLORIDE
- CAS: 62-68-0
- MF: C23H32ClNO2
- MW: 389.96
- EINECS:688-917-8
- MDL Number:MFCD00055151
- Synonyms:SKF-525A HYDROCHLORIDE >98% (PROADIFEN);ALPHA-PHENYL-ALPHA-PROPYLBENZENEACETIC ACID 2-[DIETHYLAMINO]ETHYL ESTER, HCL;ALPHA-PHENYL-ALPHA-PROPYLBENZENEACETIC ACID 2-[DIETHYLAMINO]ETHYL ESTER HYDROCHLORIDE;SK AND F 525A HYDROCHLORIDE;SKF-525A HCL;2’-diethylaminoethyl2,2-diphenylpentanoatehydrochloride ;2-diethylaminoethyl2,2-diphenylvaleratehydrochloride ;2-diethylaminoethylalpha,alpha-diphenylvaleratehydrochloride
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 100MG
- 500MG
- 1G
- ManufacturerSigma-Aldrich(India)
- Product numberP1061
- Product descriptionProadifen hydrochloride analytical standard, ≥95%
- Packaging100MG
- Price₹13087.43
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number567300
- Product descriptionSKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiti
- Packaging1G
- Price₹34619.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP1061
- Product descriptionProadifen hydrochloride analytical standard, ≥95%
- Packaging500MG
- Price₹36826.65
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P1061 | Proadifen hydrochloride analytical standard, ≥95% | 100MG | ₹13087.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 567300 | SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiti | 1G | ₹34619.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P1061 | Proadifen hydrochloride analytical standard, ≥95% | 500MG | ₹36826.65 | 2022-06-14 | Buy |
Properties
Melting point :122-123°C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 20 mg/ml)
form :White solid
color :Lustrous crystals from Me2CO/pet ether
Water Solubility :Soluble in methanol or water
Stability :Store in Freezer
EPA Substance Registry System :Proadifen hydrochloride (62-68-0)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 20 mg/ml)
form :White solid
color :Lustrous crystals from Me2CO/pet ether
Water Solubility :Soluble in methanol or water
Stability :Store in Freezer
EPA Substance Registry System :Proadifen hydrochloride (62-68-0)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
SKF 525A is a widely used, nonspecific cytochrome P (CYP)450 inhibitor that demonstrates 100% inhibition of the various CYP450 isoforms at 1-100 μM. It therefore potentiates the effects of many different drugs by inhibiting their metabolism (IC50 values in the μM range when tested using human liver microsomes). SKF 525A inhibits CYP450-dependent arachidonic acid conversion to active EET metabolites, antagonizing the recovery of functional calcium pools. It also acts as a noncompetitive inhibitor of acetylcholine nicotinic receptors (IC50 = 19 μM in mouse skeletal muscle).More related product prices
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