(S)-(+)-Ketoprofen
- ₹10900.78
- Product name: (S)-(+)-Ketoprofen
- CAS: 22161-81-5
- MF: C16H14O3
- MW: 254.28
- EINECS:606-944-5
- MDL Number:MFCD00673316
- Synonyms:(+)-hydratropicaci ;(S)-(+)-KETOPROFEN;(S)-(+)-3-BENZOYL-ALPHA-METHYLBENZENE-ACETIC ACID;[S]-2-[3-BENZOYLPHENYL]PROPIONIC ACID;3-(1-Hydrocarboxyethyl)benzophenone;Dexktoprofen;(S)-(+)-3-Benzoyl-α-methylbenzeneacetic acid, (S)-2-(3-Benzoylphenyl)propionic acid;(S)-2-(3-Benzoylphenyl)propanoic acid
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1G
- ManufacturerSigma-Aldrich(India)
- Product number471909
- Product description(S)-(+)-Ketoprofen 99%
- Packaging1G
- Price₹10900.78
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 471909 | (S)-(+)-Ketoprofen 99% | 1G | ₹10900.78 | 2022-06-14 | Buy |
Properties
Melting point :75-78 °C(lit.)
Boiling point :431.3±28.0 °C(Predicted)
Density :1.198±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; ≥10.6 mg/mL in DMSO; ≥20.55 mg/mL in EtOH
form :White solid.
pka :4.23±0.10(Predicted)
color :White to off-white
optical activity :[α]22/D +49°, c = 1 in methanol
CAS DataBase Reference :22161-81-5(CAS DataBase Reference)
Boiling point :431.3±28.0 °C(Predicted)
Density :1.198±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :insoluble in H2O; ≥10.6 mg/mL in DMSO; ≥20.55 mg/mL in EtOH
form :White solid.
pka :4.23±0.10(Predicted)
color :White to off-white
optical activity :[α]22/D +49°, c = 1 in methanol
CAS DataBase Reference :22161-81-5(CAS DataBase Reference)
Safety Information
Symbol(GHS): | |||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Danger | ||||||||||||||||||||||||||||||||||||||||||
Hazard statements: |
|
||||||||||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Ketoprofen is a non-selective, non-steroidal, anti-inflammatory drug exhibiting IC50 values of 0.5 and 2.33 μM for human recombinant COX-1 and COX-2 , respectively. Ketoprofen is commonly used in vivo as a racemic mixture of (R)- and (S)-enantiomers. (S)-Ketoprofen is a potent inhibitor of COX-1 and COX-2 (IC50s = 1.9 and 27 nM, respectively), whereas the (R)-enantiomer is 100 to 1,000 times less potent. Notably, (S)-ketoprofen is known to be formed from the (R)-enantiomer in several animal species, except in humans and guinea pigs. Also, the pharmacokinetics of ketoprofen enantiomers and their glucuronide metabolites are altered in humans with rheumatoid arthritis or renal disease.More related product prices
Citric acid 7782-24-3 3-(4-Hydroxyphenyl)propionic acid Nandrolone phenylpropionate ACETIC ACID Folic acid Ketoprofen Imidocarb dipropionate Propionic anhydride Propionic acid 107257-20-5 Allethrin 3-ACETYLBENZOPHENONE Quinic acid R-(+)-Lansoprazole Levodropropizine D(+)-Carnitine QISHTWCSIVFJBU-UHFFFAOYSA-NRelated product price
- Citric acid
₹270-98042.03 - 7782-24-3
₹4400-10467.78 - 3-(4-Hydroxyphenyl)propionic acid
₹1667.05-20773